Veterinary Biochemistry

The Department of Physiology and Biochemistry, Bombay Veterinary College was established in the year 1940, when an advanced diploma course was started.

The Department of Physiology and Biochemistry, Bombay Veterinary College was established in the year 1940, when an advanced diploma course was started.
Prior to 1940, medical officers deputed by the Government taught the subject of Physiology. The staff of the Department then consisted of one Professor and one Demonstrator. After the affiliation of the college to Bombay University and starting the degree course, the staff consisted of one Professor, one Assistant Professor and two Lecturers.
In the year 1966 the department got recognition for postgraduate studies from the Bombay University.
The Bombay Veterinary College was affiliated to Maharashtra Agricultural University in 1968 and thereafter to KonkanKrishiVidyapeeth in 1972.
 
In 2003, as per the Veterinary Council of India’s regulation, the Maharashtra Animal & Fishery Sciences University, Nagpur, created two separate departments, Department of Veterinary Physiology and Department of Veterinary Biochemistry including Clinical Biochemistry.
The departments impart training to undergraduate and graduate students. Academic programs for masters and doctoral degrees in both the disciplines of Veterinary Physiology and in Veterinary Biochemistry are offered by the departments.
Besides the academic programs, the departments’ conduct basic and applied research and technology transfer in Veterinary and Animal Sciences with emphasis on animal health and production.  The department also offers diagnostic facilities of Veterinary Laboratory Diagnostics to the Teaching Veterinary Clinical Complex, Zoo, National Park, Dairy Farms, Field Veterinarians and Pet Owners.
 First Year B.V.Sc& A.H.
 
Semester I: VPB 112 (General Veterinary Biochemistry)
Credit Hours: 1 + 1 = 2
Tentative lecture schedule
 
Lecture
No.
Topic
1 & 2
Scope and importance of biochemistry. Buffer system and pH. Dissociation of and Henderson – Hasselbalch equation
3 & 4
Structure of cell membranes and transport across cell membranes. Donnan membrane equilibrium
Biochemistry of carbohydrates: Biological significance (structure and properties) of:
5
Monosaccharides (ribose, glucose, fructose, galactose, mannose and amino sugars)
6
Disaccharides (maltose, isomaltose, lactose, sucrose and cellobiose
7
Polysaccharides (starch, dextrins, dextrans, glycogen, cellulose, inulin, chitin)
8
Mucopolysaccharides including bacterial cell wall polysaccharides
Biochemistry of lipids:
9 & 10
Properties (structure) and biological significance of simple, compound and derived lipids and lipoproteins
11
Structure and functions of prostaglandins. Chemistry of bile and bile salts
12
Amino acids: Classification and structure of neutral basic and acidic amino acids
13
Properties of amino acids: amphoteric nature, optical activity and peptide bond formation
14
Structure properties, biological significance and chemical reactions of proteins
Biochemistry of nucleic acids
15
Chemistry of purines and pyrimidines, nucleosides and nucleotides. Biological significance of nucleosides and nucleotides
16
Structures and functions of deoxyribonucleic acid (DNA) and a typical ribonucleic acid

 

First Year B.V.Sc& A.H.
Semester II: VPB 122 (Veterinary Intermediary Metabolism)
Credit Hours: 2 + 1 = 3
Tentative lecture schedule

 

Lecture
No.
Topic
1 & 2
Enzymes: Definition, classification and EC numbering of enzymes. Coenzymes, cofactors &isoenzymes. Enzyme units: International units, katal, turnover number & specific activity.
3 & 4
Properties: Protein nature, Enzyme-substrate complex formation, Modern concept of enzyme specificity of enzyme action: substrate specificity, Group specificity, stereo specificity, optical specificity.
5
Factors influencing enzyme action: Effects of temperature, pH, concentration of substrate and enzyme; Enzyme inhibition: Competitive, non competitive, uncompetitive and suicidal inhibition allosteric enzymes.
6 & 7
Biological Oxidation: Enzymes and coenzyrnes involved in oxidation and reduction viz. Oxidoreductase, Oxidases, oxygenases, dehydrogenases, Hydroperoxidases& cytochromes.
8 & 9
Respiratory chain / electron transport chain, oxidative phosphorylation, inhibitors, uncouplers and other factors influencing electron transport chain
Carbohydrate metabolism along with bioenergetics:
10
Glycolysis
11
Kreb’s cycle along with energetics
12
Glyoxilate cycle, HIVIP shunt. Gluconeogenesis
13
Cori cycle, Glycogenesis, Glycogenolysis
14
Hormonal control of carbohydrate metabolism & regulation of blood sugar.
Lipid metabolism with bioenergetics:
15
Beta oxidation of fatty acid, Ketone body formation
16
Biosynthesis of fatty acids. Triacylglycerol metabolism
17
Phospholipids & lipoprotein metabolism
Protein metabolism:
18
Biosynthesis of proteins
19
Degradation of protein: deamination, transamination & decarboxylation of amino acids
20
Ammonia transport and urea cycle.
21 & 22
Nucleic acids: Metabolism of purines and pyrimidines
23
DNA & RNA biosynthesis
24
Integration of metabolism
25
Metabolic functions of macro nutrients
26
Metabolic functions of micro nutrients
Metabolic functions of lipid soluble vitamins:
27
Metabolic functions of Vitamin A & E
28
Metabolic functions of Vitamin D & K
Metabolic functions of water soluble vitamins:
29
Vitamin C
30
Thiamine, Riboflavin, Niacin & Pyridoxine,
31
Pantothenic acid, Folic acid & Cynocobalamin.
32
Use of isotope in metabolic studies.

 

Third Year B.V.Sc& A.H.
Semester VI: VPB-321 Animal Biotechnology Credit Hours: 2 + 1 = 3
Tentative lecture schedule

 

Lecture
No.
Topic
Endocrinology
1
Definitions, basic concepts and scope of animal biotechnology.
2 & 3
Recombinant DNA technology: Principles, procedures and applications
4 & 5 (Micro)
Gene cloning, vectors and expression vectors. New generation vaccines:
subunit, recombinant and recombinant vectored vaccines
6
Animal tissue culture: Principles, procedure and application
7 & 8
Transformation and cell lines: Principles, procedure and application
9
Polymerase chain reaction (PCR) and its application in molecular diagnosis. DNA probes, nucleic acid hybridization
10 & 11
Transfection, Transgenic animal and biopharming
12 & 13
Construction of genomic library and cDNA library
14 & 15
DNA sequencing – genome, sequencing and mapping
16
Marker assisted selection and gene banking
17
Nutritional biotechnology including bioconversion of lignocellulose, genetic manipulation of microbes for improved feed utilization and health
18 & 19
Principles of transfer of nucleic acids and proteins (Southern, Northern and Western blotting), DNA fingerprinting and its applications
20
Tumour markers and acute phase proteins
21
Hybridoma and monoclonal antibodies
22
Fermentation process
23
Technologies for milk, meat and leather
24 (Gyn)
Biotechnological application in animal improvements: Embryo biotechniques, in vivo embryo production, Embryo micromanipulation
25
In vitro embryo production, Embryo sexing
26
Embryo preservation, Embryo cloning
27 & 28
Ethics and regulatory issues in biotechnology, IPR, Bioinforrnatics

 

Fourth year B.V.Sc& A.H.

Semester VII
VPB-411 (0+1=1)
Veterinary Clinical Biochemistry
This course is conducted in collaboration with other clinical and Para clinical departments like Medicine, Pathology, Parasitology, Microbiology etc.

These courses come under Diagnostic Laboratory Section under TVCC
Semester VII
VCP-411 (0+5=5)
Veterinary Clinical practice

This course is conducted in collaboration with other clinical and Para clinical departments like Medicine, Pathology, Parasitology, Microbiology etc.

Semester VIII

VCP-421 (0+5=5)
Veterinary Clinical practice

This course is conducted in collaboration with other clinical and Para clinical departments like Medicine, Pathology, Parasitology, Microbiology etc.

Fifth year B.V.Sc& A.H.
VCP-511(0+5=5)
Semester IX

Veterinary Clinical practice

Thiscourseis conducted in collaboration with other clinical and Para clinical departments like Medicine, Pathology, Parasitology, Microbiology etc

First Year M.V.Sc.
Veterinary Biochemistry
Semester I: VBC 601 (Chemistry of Animal Cell)
Credit Hours: 2 + 0 = 2

 

Tentative lecture schedule
Lecture No.
                                                      Topics
UNIT I
1]         Pre-biotic world and chemical evolution.
2-3]      Cellular architecture and molecular organization of cell.
4]         Metabolic functions of cell.
UNIT II
5]         Thermodynamics,
6]         Chemical equilibrium and standard state.
7-8]      Living cell as steady state and open system obeying laws of thermodynamics.
9]         Minimum energy conformation.
10-11]  Quantum mechanical calculation. 
12]       ∆G and ATP.
UNIT III
13]       Properties of water.
14]       Homeostasis
15]       Colloids and determination of size of colloidal particles.
16]       Brownian motion, precipitation, mutual precipitation and protective colloids.
17]       Dialysis and ultrafiltration
18-19]  Donnan’s theory of membrane equilibrium, membrane hydrolysis
20-21]  Application of physicochemical laws in living organisms (osmosis, viscosity, surface forces, adsorption, etc.)
22]       Bronsted’s theory of Acids and Bases, titratable and actual acidity.
23]       Determination of pH, Henderson – Hasselbalch Equation
24]       Buffers and factors affecting buffering capacity.
25]       Bicarbonate buffer system, Phosphate buffer system,
26]       Protein buffer system and Haemoglobin buffer system.
27]       Amino acid buffer system, buffer of RBC’s and plasma.
28-29]  Chemical basis of oral and parental fluid/electrolyte therapies
30]       Bacterial toxigenic diarrhoeas
31]       Problem solving – Lecture1 to12.
32]       Problem solving – Lecture13 to30.

 

Semester I: VBC 602 (Techniques in Biochemistry)
Credit Hours: 0 + 2 = 2

 

Tentative lecture schedule
Practical No.
                                                      Topics
1]         Solving problems using Henderson–Hasselbalch equation regarding pH.
2]         Determination of pKa and buffer concentration
3]         Calculation of normality.
4]         Principle and application of colorimetry and spectrophotometry.
5]         Application NMR-X ray crystallography. (Theoritocal back ground).
6]         Principle and application of Paper Chromatography.
7]         Principle and application of Thin Layer Chromatography.
8]         Principles and applications of Column chromatography.
9]         Partition chromatography and adsorption co-efficient.
10]       Quantitative and qualitative chromatography of amino acids.
11]       Quantitative and qualitative chromatography of lipids.
12]       Quantitative and qualitative chromatography of sugars. (Theoritocal back ground)
13]       Elution following Column chromatography. 
14]       Gas chromatography. (Theoritocal back ground)
15]       Packing of column and choice of detectors and densitometry.
16]       Application of electrophoresis. Electrophoresis of proteins.
17]       Electrophoresis of nucleic acids.
18]       Use of sodium dodecyl sulfate and molecular weight determination.
19]       Use of sodium dodecyl sulfate and molecular weight determination.
20]       Densitometry procedures and quantitative assays.
21]       Immuno-electrophoresis and its applications.
22-23]  Preparation of agar/agarose gel for immuno-electrophoresis.
24]       Isoelectrofocussing.
25]       Isotacophoresis.
26]       Molecular sieving and its application in Biochemistry.
27]       General properties of dextran, acrylamide, agar and other media used for gel filtration.
28]       Ultracentrifugation– its principle and use.
29-30]  Preparative analytical and density gradient ultracentrifugation.
31]       Fractionation of sub-cellular components.
32]       Molecular weight determination using ultracentrifuge.

 

Semester I: VBC 603 (Applications of Genomics and Proteomics in Molecular Biology)
Credit Hours: 2 + 0 = 2

 

Tentative lecture schedule
Lecture No.
                                                      Topics
UNIT I
1]         Nucleotides and nucleic acids.
2]         High order structures, cohesions and condensins in chromosome structure.
3]         SMC proteins and sequencing.
4]         Mutation and evolution.
5]         DNA libraries.
6]         Bacterial RNA polymerase.
7]         RNA interference.
8]         DNA replication.
9]         RNA synthesis.
10]       Control of gene expression.
11]       DNA microarrays/chips.
UNIT II
12]       PCR and factors affecting it.
13]       r-DNA technology in improving domestic animals.
14]       RELP, Gene and gene products.
15]       Genetic changes in hereditary diseases, cancer and detection using DNA probes.
16]       Gene Therapy, DNA vaccines, anti-tumor antibodies.
17]       Telomerases and Topoisomerases in treatment of diseases.
18]       Staphylococcus resistance to erythromycin.
UNIT III
19]       Peptide bonds and protein structure.
20]       Acid-base properties and stereochemistry of proteins.
21]       Side chain modifications and biological activities of proteins.
22]       Green fluorescent protein and use.
23]       Polypeptide diversity, protein purification and analysis.
24]       Protein sequencing, reconstructing the protein sequence.
25]       Gene duplication and protein families.
26]       Protein modules, combinatorial peptide libraries folding.
27]       Structural bio-informatics.
28]       Protein structure prediction, designing and Proteomics.
29]       Drug molecules, myoglobin and haemoglobin.
30]       Mechanism and co-operativity in Hb.
31]       High altitude adaptation in ruminants and equines.
32]       Use of amino acid analysis in disease diagnosis.

 

Semester I: VBC 604 (Biochemistry of Biomolecules: Carbohydrates Lipids and Membrane’s Structure)
Credit Hours: 2 + 0 = 2

 

Tentative lecture schedule
Lecture No.
                                                      Topics
UNIT I          
1]         Carbohydrates: structure
2]         Glycoconjugates in cell surface, extra cellular matrix,
3]         Sugar code functions, peptidoglycan-specific antibiotics
4]         Cellular effects of Insulin
5]         Glucose supply and removal
6]         Ruminal fermentation
7]         Role of liver
8]         Glucose tolerance, indirect monitoring of blood glucose
9]         Ketone bodies
UNIT II         
10]       Lipid classification,
11]       Metabolism of LCFA, TAG, PL,
12]       Sphingolipids, cholesterol, lipoproteins
13]       Regulation of lipid metabolism in fed and fasted states
14]       Regulation of FA oxidation, fas as regulatory molecules
15]       Glucose production and fas in type II diabetes
16]       Ketone bodies as fuel.
UNIT III       
17]       Lipid bilayers, lipid motility,
18]       Integral membrane proteins, lipid linked proteins, peripheral membrane proteins
19]       Fluid mosaic model, membrane skeleton,
20]       Lipid asymmetry, vesicle trafficking
21]       Secretory pathway, membrane rafts
22]       Caveolae fusion
23]       Lung surfactant
24]       Structure of bacterial rhodopsin
25]       Thermodynamics of membrane transport
26]       Ionophores, porins, ion channels, aquaporins, transport proteins
27]       P and F types (Na+ – K+ ) atpases
28]       Ca , Ion–gradient, Gap Junction,
29]       Cl–HCO-  exchanger
30]       Cardiac  2+3 glycosides
31]       Abnormalities in cell membrane fluidity
32]       Haemolyticanaemia

 

Semester I: VBC 604 (Biochemistry of Biomolecules: Carbohydrates Lipids and Membrane’s Structure)
Credit Hours: 2 + 0 = 2

 

Tentative lecture schedule
Lecture No.
                                                      Topics
UNIT I          
1]         Carbohydrates: structure
2]         Glycoconjugates in cell surface, extra cellular matrix,
3]         Sugar code functions, peptidoglycan-specific antibiotics
4]         Cellular effects of Insulin
5]         Glucose supply and removal
6]         Ruminal fermentation
7]         Role of liver
8]         Glucose tolerance, indirect monitoring of blood glucose
9]         Ketone bodies
UNIT II         
10]       Lipid classification,
11]       Metabolism of LCFA, TAG, PL,
12]       Sphingolipids, cholesterol, lipoproteins
13]       Regulation of lipid metabolism in fed and fasted states
14]       Regulation of FA oxidation, fas as regulatory molecules
15]       Glucose production and fas in type II diabetes
16]       Ketone bodies as fuel.
UNIT III       
17]       Lipid bilayers, lipid motility,
18]       Integral membrane proteins, lipid linked proteins, peripheral membrane proteins
19]       Fluid mosaic model, membrane skeleton,
20]       Lipid asymmetry, vesicle trafficking
21]       Secretory pathway, membrane rafts
22]       Caveolae fusion
23]       Lung surfactant
24]       Structure of bacterial rhodopsin
25]       Thermodynamics of membrane transport
26]       Ionophores, porins, ion channels, aquaporins, transport proteins
27]       P and F types (Na+ – K+ ) atpases
28]       Ca , Ion–gradient, Gap Junction,
29]       Cl–HCO-  exchanger
30]       Cardiac  2+3 glycosides
31]       Abnormalities in cell membrane fluidity
32]       Haemolyticanaemia

 

Semester I: VBC 605 (Enzyme Catalysis, Kinetics, Inhibition and Regulation)
Credit Hours: 2 + 0 = 2

 

Tentative lecture schedule
Lecture No.
                                                      Topics
UNIT I
1]         Introduction to the enzymes their classification and functions.
2]         Enzyme activation energy.
3]         Mechanisms of acid-base reaction co-ordination.
4]         Mechanisms of covalent reaction co-ordination.
5]         Mechanisms of metal ion reaction co-ordination. 
6]         Proximity and orientation effects.
7]         Preferential transitional state binding. 
UNIT II
8]         Chemical kinetics of reaction.
9]         Enzyme kinetics of reaction.
10]       Kinetic data analysis.
11]       Bisubstrate reactions.
12-13]  Competitive, Uncompetitive, Mixed inhibitors.
14]       Allosteric regulation.
15]       Enzymes in drug designing.
16]       Enzymes in drug discovery.
17]       Bioavailability and toxicity.
18]       Enzymes in clinical trials. 
19]       Cytochrome P450 and adverse drug reactions.
20]       Synthesis of bacterial peptidoglycans.
21]       Synthesis of Oxygenases.
22]       Synthesis of mixed function oxidases.
23]       Enzyme linked diagnostics.
UNIT III
24]       Lysozymes.
25]       Serine proteases.
26]       Physiology and tumor cell metastasis.
27]       Nerve poisons.
28]       Blood coagulation cascade.
29]       Equine immuno-deficiency enzyme inhibitors.
30]       Suicide activators (DFMO for inhibition of ornithine decarboxylases in trypanosomiasis).
31]       Problem solving – Lecture1 to12.
32]       Problem solving – Lecture13 to30.

 

Semester II: VBC 606 (Metabolism – I: Carbohydrates and Lipids)
Credit Hours: 2 + 0 = 2

 

Tentative lecture schedule
Lecture No.
                                                      Topics
UNIT I          
1]         Metabolic control,
2]         Analyses for enzymes limiting the flux through a pathway.
3]         Trophic strategies,
4]         Universal mapping of metabolic pathways
5]         Thermodynamic relationships. G,
6]         ATP and phosphoryl group transfer
7]         Coupled reactions, thioesters,
8]         NAD+ and FAD.
UNIT II         
9]         Overview of carbohydrate and lipid cycles,
10]       Control of glycolysis
11]       Glycolysis in cancer cells
12]       Control of pentose phosphate pathways
13]       Deficiency of glucose-6-phosphate dehydrogenase
14]       Control of glycogen metabolism
15]       Control of gluconeogenesis
16]       GSD.
17]       Regulation of citric acid cycle
18]       Pathways that use citric acid intermediates
19]       Sugar interconversions and nucleotide – linked sugar formation
20]       Disorders associated with impairment of metabolism
UNIT III       
21]       Electron transport and oxidative phosphorylation
22]       Generation of heat by uncoupling in brown adipose tissue.  
UNIT IV
23]       Regulation of fatty acid metabolism
24]       Inhibitors of fatty acids biosynthesis
25]       Sphingolipid degradation
26]       Lipid storage disease
27]       Regulation of cholesterol synthesis
28]       PGs in NSAID
29]       Leukotrienes
30]       HETEs
31]       Hypersensitivity
32]       Influence of glucose metabolism on lipid metabolism

 

Semester II: VBC 607 (Metabolism – II: Nucleic Acids and Amino Acids)
Credit Hours: 2 + 0 = 2

 

Tentative lecture schedule
Lecture No.
                                                      Topics
UNIT I          
1]         Overview of pathways of amino acid
2]         Overview of pathways of nucleic acid metabolism
3]         Lysosomal degradation
4]         Ubiquitin
5]         Proteosome
6]         Breakdown of amino acids
7]         Heme biosynthesis and degradation
8]         Biosynthesis of physiologically active amines
9]         Nitric oxide
10]       Homocystein as marker of disease
11-12]  Diseases of amino acid metabolism
13]       Porphyrias
UNIT II         
14]       Nucleotide synthesis and degradation
15]       Inhibition of thymidylate synthesis in cancer therapy
16]       Mutation in coenzyme binding sites and diseases
17]       Forces stabilizing NA structure
18]       Restriction endonucleases
19]       Small inhibitory RNAs
20]       Chromatin organization
21]       Inhibitors of topoisomerases as antibiotic
22]       Anti-cancer agents interfering with purine and pyramidine metabolism
UNIT III        
23]       Viral nucleic acids
24]       DNA damage and repair
25]       Telomerase
26]       Ageing and cancer
27]       Topoisomerases as drug targets
28]       Chemotherapy can target precursors of DNA synthesis
29]       Antibiotics and toxins that target RNA polymerase
30]       Lysosomal enzymes
31]       Gout
32]       Diseases in purine and pyrimidine nucleotide metabolic impairment

 

Semester II: VBC 608 (Metabolism – III: Integration and Regulation)
Credit Hours: 2 + 0 = 2

 

Tentative lecture schedule
Lecture No.
                                                      Topics
UNIT I          
1]         Regulation of carbohydrate metabolism
2]         Regulation of lipid metabolism
3]         Regulation of protein metabolism
4]         Regulation of nucleic acid metabolism
5]         Integration all metabolic pathways
UNIT II
6]         Organ specialization in fuel metabolism: Brain, muscle
7]         Organ specialization in fuel metabolism: adipose tissue, liver, kidney
8]         Inter organ metabolic pathways
9]         Hormonal control of fuel metabolism
10]       Tracing metabolic fates perturbing the system
UNIT III       
11]       Signal transduction, gated ion channels
12]       G-proteins
13]       Adenylatecyclase, cGMP,  Ca2+
14]       Receptor tyrosine kinase
15]       Protein phosphatases
16]       Interaction of Ca2+ with phosphoserine/tyrosine
17]       Integrations of proteins/ messengers in signal transduction
18]       Drugs and toxins
19]       Cell cycle and CDKs that affect cell signaling
UNIT IV       
20]       Oncogenes and cancers
21]       Mitochondrial genes and diseases
22]       Reactive oxygen species
23]       Cyanide and arsenic poisoning
24]       Metabolic inter-relationships in obesity, diabetes, and cancer
25]       Metabolic inter-relationships in aerobic and anaerobic exercise in horses
26]       Metabolic inter-relationships in pregnancy, lactation and stress injury
27]       Mitochondria in apoptosis and oxidative stress, cell suicide
28]       Liver diseases
29]       Renal diseases
30]       Acid-base balance
31]       Metabolic/sensory transduction in nervous tissue
32]
Vision, blood coagulation

 

Semester II: VBC 609 (Central Dogma and Protein)
Credit Hours: 2 + 0 = 2

 

 
Tentative lecture schedule
Lecture No.
                                                      Topics
UNIT I            
1]         Overview of transcription and translation in eukaryotes
2]         Collision between DNA polymerase and RNA polymerase
3]         Inhibitors of transcription
4]         Introns
5]         Evolution and expansion of the genetic code
UNIT II
6]         The effects of antibiotics and toxins on protein synthesis     
7]         X – chromosome inactivation
8]         Eukaryotic gene expression
9]         Protein targeting
UNIT III         
10]       Actin structure
11]       Microfilament dynamics
12]       Actin-myosin reacting cycle
13]       Tubulin dimmer
14]       Microtubules dynamics
15]       Kinensins and dyeins
UNIT IV         
16]       Antigen-antibody binding
17]       Cytokines
18]       Principles of immunochemical methods
19]       Agglutination, precipitation
20]       Typing of major histo-compatibility antigens
21]       Blood group substances in farm animals
UNIT V           
22]       Proteins as infectious agents (prions – BSE).
23]       Protein misfolding and aggregation
24]       Plasma proteins, synthesis, functions
25]       Influences of physiological factors and inflammation on proteins
26]       Dysproteinemias
27]       Defects in collagen synthesis
28]       Transmissible multiple drug resistance
29]       Transcription factors and cardiovascular diseases
30]       Transferrin
31]       Lactoferrin
32]       Ferritin and Ceruloplasmin

 

Semester II: VBC 610 (Clinical Biochemistry of Animals)
Credit Hours: 2 + 1 = 3

 

Tentative lecture schedule
Lecture No.
                                                      Topics
UNIT I
1-3]      Disturbances of gastro-intestinal function- Irritable Bowel Syndrone Ulcerative Collitis
4-6]      Disturbances of rumen function. – Bloat (Tympany), urea poisoning, acute rumen indigestion, Lactic acidosis
7-8]      Pickled pigs and malignant hyperthermia.
9-10]    Diagnosis of neuromuscular disorders. Eg. mitochondrialdiseases
UNIT II
11]       Myocardial infarction,
12]       Respiratory distress syndrome.
13-14]  Primary renal dysfunctions and test, 
15-16]  Doping. Problems in game horses.
UNIT III
17-18]  Enzymes of diagnostic importance.
19-20]  Toxicity of ammonia in animals.Genetic defects in urea cycle.
21]       Lysosomal storage diseases.
22-23]  ATP synthase inhibitory protein during ischemia. Ischaemic – reperfusion injury.
UNIT IV
24-25]  Molecular oncology and tumor markers.
26]       CSF characteristics in diseases.
27]       Clinical Biochemistry in toxicology.
28]       Glycosylated hemoglobin, HbA1c, fructosamine.
29]       Deranged glucose metabolism in cancerous tissue.
30]       Free Radical damage.
31]       Problem solving for lectures 1-16
32]       Problem solving for lectures 17-30

 

Semester III: VBC 606 (Biochemical Basis of Diseases of Domestic Animals)

 

Credit Hours: 2 + 0 = 2
Tentative lecture schedule
Lecture No.
                                                      Topics
UNIT I
1]         Diabetes mellitus
2-3]      Hyperinsulemia, galactosemia, hypoglycaemia of baby pigs,
4]         Glycogen Storage Disease.
5]         Carbohydrate balance in ruminants.
6]         Biochemical alterations in body fluids of ruminants in hypoglycaemia,
7]         Ruminant ketosis. 
UNIT II
8]         Hypercholesterolemia,
9]         Atherosclerosis,
10-11]  hyperlipidemia in canine, feline, equine.
12]       Pathophysiology of ketonemia.
13-14]  Ketosis associated with fasting, diabetes, pregnancy, lactation and post exercise.
UNIT III
15]       Anemias of the newborn,
16-17]  Cytosolic enzyme deficiencies and membrane abnormalities in erythrocytes.
18]       Porphyrins and porphyrias.
19]       Disorders of iron metabolism,
21]       Neutrophil function defects and its testing.
22]       Equine immuno-deficiency.
UNIT IV
23-24]  Hepatic insufficiencies and its laboratory assessment
25-26]  Pancreatitis and insuffiency
27-28]  Metabolic diseases of Ca, P, Mg metabolism
29]       Iron overload and injection
30]       Inorganic polyphosphate metabolism
31]       Problem solving for lectures 1 – 16
32]       Problem solving for lectures 17 – 30

 

Semester III: VBC 612 (Endocrinology and Reproductive Biochemistry)
Credit Hours: 2 + 0 = 2

 

Tentative lecture schedule
Lecture No.
                                                      Topics
UNIT I
1-2]      Mechanism of hormone action
3]         Receptor binding,
4-6]      Biosynthesis of hormones and factors
7-8]      Metabolic aspects in physio-pathology of hormones, factors, and minerals. 
UNIT II
9-10]    Metabolic functions of the hormones of the hypothalamus
11-12]  Metabolic functions of pituitary
13]       Metabolic functions of Thyroid
14]       Metabolic functions of parathyroid
15]       Metabolic functions of pancreas
16-17]  Metabolic functions of adrenal
18]       Metabolic functions of pineal
19]       Metabolic functions of ovaries
20]       Metabolic functions of testes
21-22]  Biochemistry of prostaglandins and related agents.
23-24]  Clinical endocrine aspects in production in domestic animals
25-26] Clinical endocrine aspects in reproduction status in domestic animals
27-28]  Clinical endocrine aspects in production in poultry
29-30] Clinical endocrine aspects in reproduction status in poultry
31]       Problem solving for lectures 1-15
32]       Problem solving for lectures 15-30

 

Semester III: VBC 613 (Biochemical Basis of Animal Production)
Credit Hours: 2 + 1 = 3

 

Tentative lecture schedule
Lecture No.
                                                      Topics
UNIT I
1-2]      Chemistry of milk lipids,
3-4]      Chemistry of milk proteins,
5-6]      Chemistry of milk carbohydrates,
7-8]      Chemistry of milk minerals,
9-10]    Chemistry of milk vitamins,
11-12]  Chemistry of milk pigments and enzymes.
13-14]  Structure of milk lipids, fat globular membranes, modification of milk fat.
15-16]  Milk proteins – casein, amino acid composition, whey proteins, immunoglobulins, genetic polymorphism.
17-18]  Carbohydrates: structure and sweetness.
UNIT II
19-20]  The biochemistry controlling postmortem energy metabolism mechanisms.
21-22]  Application of genomic technologies to the improvement of meat quality of farm animals.
23-24]  Identification of meat quality parameters by proteomics.
25-26]  Application of proteomics to understand the molecular mechanisms behind meat quality.
27-28]  Oxidative stability of post mortem muscles from sheep of various ages. 
UNIT III
29-30]  Metabolic demands of draft animals, and biochemical aspects of work and kinesiology.
31]       Problem solving for lectures 1-15
32]       Problem solving for lectures 15-30
 

List of Research Topics of M.V.Sc Theses

 

 

Sr.  No.
Name of the Student
Title of the Thesis
Year
University
1.
Dr. V. G. Joshi
Some haematological observations on Rathi cows
1968
Bombay
2.
Dr. Y. G. Gadgil
Studies on blood serum proteins of Rathi cows
1968
Bombay
3.
Dr. (Mrs.) B. A. Talvelkar
Studies on certain aspects of eggs in the pure bred strains of White Leghorn, Australorp and their cross White Austro
1970
MPKV
4.
Dr. K. B. Puranik
Studies on blood serum proteins of crossbred cow calves and Murrah buffalo calves by starch agar gel electrophoresis
1970
MPKV
5.
Dr. G. D. Behre
Studies on blood serum proteins of chickens of exotic breeds and of local (Desi) chickens.
1970
MPKV
6.
Dr. M. V. Chavan
Studies on the use of biostimulator (spleen extract) in broilers
1975
KKV
7.
Dr. S. J. Pardikar
Haematological and biochemical studies in sheep and goats
1976
KKV
8.
Dr. U. K. Parchure
Studies on serum proteins in Bannur sheep
1978
KKV
9.
Dr. M. Rafi
Studies on some serum electrolyte levels in Bannur sheep
1986
KKV
10.
Dr. (Ms.) A. J. Mhatre
Studies on some haematological and biochemical parameters in broilers under different temperature regimes.
1986
KKV
11.
Dr. P. B. Bhangale
A study on effects of some climatic factors on physiological responses in Gir and crossbred lactating cows
1986
KKV
12.
Dr. M. D. Patil
Studies on haematology of Murrah buffaloes
1989
KKV
13.
Dr. Mir Manzoor
Concentration of some major elements in blood plasma and milk of crossbred lactating cows during different stages of lactation
1990
KKV
14.
Dr. S. D. Dhande
Immunoglobulin levels in lacteal secretions of indigenous and crossbred cows in early lactation
1992
KKV
15.
Dr. S. W. Bonde
Passive immune status in neonatal crossbred calves
1992
KKV
16.
Dr. B. V. Jichkar
Serum immunoglobulin levels in crossbred cows
1992
KKV
17.
Dr. D. S. Jagdale
Studies on estradiol – 17ß, progesterone and lipid profile in crossbred cows
1993
KKV
18.
Dr. S. H. Dalvi
Blood serum thyroid hormone concentration during late pregnancy, parturition and early lactation of crossbred cows
1993
KKV
19.
Dr. S. M. Deshpande
Studies on macro elements during gestation and early postpartum period in Gir and crossbred cows
1994
KKV
20.
Dr. P. D. Bansode
Effect of oxytocin on milk production and its composition in crossbred cows
1994
KKV
21.
Dr. N. S. Sonawane
Effect of bovine somatotropin on blood lipid profile in lactating crossbred cows.
1995
KKV
22.
Dr. S. K. Bhere
Effect of administration of bovine somatotropin on milk yield, milk composition, feed intake and body weights of lactating crossbred cows
1996
KKV
23.
Dr. V. D. Garje
Effect of exogenous bovine somatotropin on major elements of milk in lactating crossbred cows
1996
KKV
24.
Dr. L. R. Gadhave
Studies on serum protein profile during gestation and early postpartum period in Gir and crossbred cows
1997
KKV
25.
Dr. S. D. Ingole
Serum enzyme profile during gestation and early lactation in Gir and crossbred cows
1997
KKV
26.
Dr. (Ms.) S. V. Bharucha
Effect of bovine somatotropin on blood serum proteins in lactating crossbred cows
1997
KKV
27.
Dr. B. V. Atak
Serum enzyme profile during growth in Gir and crossbred calves
1998
KKV
28.
Dr. S. P. Patil
Studies on serum protein profile during growth in Gir and crossbred calves
1998
KKV
29.
Dr. (Ms.) S. V. Bhide
Effect of induced hypothyroidism on blood biochemical constituents in goats
1998
KKV
30.
Dr. N. B. Vadnere
Effect of induced hypothyroidism on haematology and thyroid hormones concentration in goats
1998
KKV
31.
Dr. M. N. Harlikar
Trace element profile during growth in crossbred calves and heifers
1999
KKV
32.
Dr. (Ms.) A. S. Lourenco
Haematological profile in crossbred calves and heifers
1999
KKV
33
Dr. R. R. Patil
Trace element profile during gestation and lactation in crossbred cows
2000
KKV
34
Dr. Y. S. Mehere
Haematological and trace element profile during peripartum period in crossbred cows
2000
KKV
35
Dr. (Ms.) A. A. Pimputkar
Haematological profile during gestation and lactation in crossbred cows
2000
KKV
36
Dr. K. B. Bahiram
Mineral profile during growth in crossbred calves and heifers
2001
BSKKV
37
Dr. D. N. Paikrao
Mineral profile during gestation, peripartum period and lactation in crossbred cows
2001
BSKKV
38
Dr. R. R. Dhotre
Comparative study of serum testosterone profile and seminal characteristics of cow and buffalo bulls
2001
BSKKV
39
Dr. S. B. Nalavade
Comparative study of serum lipid profile in buffalo bulls and cow bulls
2002
MAFSU
40
Dr. P. L. Gade
Serum trace elements profile in cow bull and buffalo bull
2002
MAFSU
41
Dr. S. Y. Bidye
Concentrations of serum thyroxine, triiodothyronine and thyroid stimulating hormone in buffalo and cow bulls
2002
MAFSU
42
Dr. T. P. Bawane
Serum Inhibin, FSH, LH concentrations and seminal plasma Inhibin activity in buffalo and cow bulls
2003
MAFSU
43
Dr. (Ms.) G. V. Parab
Comparative study of serum protein profile in buffalo bulls and cow bulls
2003
MAFSU
44
Dr. S. R. Nikam
Seminal plasma lipid profile in buffalo and cow bulls
2003
MAFSU
45
Dr. S. B. Kancharla
Seminal plasma trace element profile in buffalo and cow bulls
2003
MAFSU
46
Dr. (Ms.) S. D. Borkar
Effect of inhibin immunization on seminal characteristics in buffalo bulls
2004
MAFSU
47
Dr. S. N. Itankar
Effect of Inhibin immunization on haematological parameters in buffalo bulls
2004
MAFSU
48
Dr. S. K. Aghadate
Effect of Inhibin immunization on serum electrolytes concentration in buffalo bulls
2005
MAFSU
49
Dr. D. V. Ingavale
Effect of Inhibin immunization on serum thyroxine, triiodothyronine and thyroid stimulating hormone in buffalo bulls
2005
MAFSU
50
Dr. (Ms.) S.D. Konkar
Effect of inhibinimmunisation on serum protien profile in buffalo bulls
2005
MAFSU
51
Dr. (Ms.) S. D. Dhaware
Follicular fluid biochemical profile of buffalo
2006
MAFSU
52
Dr. (Ms.) Shiny Joy
Follicular fluid protein profile in buffalo
2006
MAFSU
53
Dr. (Ms) V. K. More
Electrolyte concentration in follicular fluid of sheep
2006
MAFSU
54
Dr. (Ms.) A. D. Gandhe
Serum Protein profile during lactation in buffalo
2007
MAFSU
55
Dr. P. M Tripathi
Serum lipid profile during lactation in buffalo
2007
MAFSU
56
Dr. (Ms.) V. M. Tekade
Serum Protein profile during early pregnancy in buffaloes
2009
MAFSU
57
Dr. SushantaDebbarma
Serum progesterone and thyroid hormone profile during gestation and early post partum period in goats
2010
MAFSU
58
 
 
 
 
 
Dr. T. R. Mahanwar
Serum enzyme profile during gestation and early post partum period in goats
 
2010
 

List of Research Topics of Ph.D. Theses

 

Sr. 
Sr.  No.
Name of the Student
Title of the Thesis
Year
University
1.
Dr. B. A. Kulkarni
Studies on Immunoglobulins in Indian Buffaloes (Bosbubalusbubalis)
1971
Bombay
2.
Dr. (Mrs.) A. M. Mantri
Studies on the Leutinizing Hormone (LH) in Domestic Fowl (Gallus Domesticus)
1977                  
KKV
3.
Dr. V. G. Joshi
Study of Thyroid Function in Different Strains of Fowl in Relation to Growth Rate and Laying Performance
1978
KKV
4.
Dr. (Mrs.) B. A. Talvelkar
Studies on Serum Leutinizing Hormone and Prolactin Levels in Purebred Gir and Crossbred Dairy Animals
1980  
KKV
5
Dr. B. T. Deshmukh
Influence of Frequency of Feeding and Milking on the Secretion of Milk in Lactating Crossbred Cows
1985
Kurukshetra
7
Dr. (Mrs.) A. S. Nagvekar
Profiles of serum Somatotropin, Gonadotropin, Ovarian Steriods and Thyroidal Hormones during gestation of Buffalo
2009
MAFSU
1.     Talvelkar, B. A. (1967). The effect of molting on some of the egg qualities in White Leghorn and Rhode Island Red birds.B.V.C.M. 14 :  16-19.
 
2.     Talvelkar, B. A.  (1968). Behavior of the wild animals.B.V.C.M. 15 :  61-63 
 
3.     Talvelkar, B. A. and Kulkarni, M. V. (1969) .Studies on Growth of White Leghorn Chicks.B.V.C.M. 16: 40-42
 
4.     Raikar, R.K., Talvelkar, B. A. and Joshi, V. G. (1975)A Preliminary report on some electrolytes in broilers.B.V.C.M.   20 : 45-47. 
 
5.     Talvelkar, B. A., Kulkarni, B. A. and Raikar, R. K. (1980). Haematological Studies in Gir and Crossbred Cows.Indian Vet. J. 57 : 640-643
 
6.     Talvelkar, B. A., Raikar, R. K., Sheth, A.R. and Gadgil, B. A. (1981).Serum LH Levels in Fertile Vs Infertile Inseminations in Purebred and Crossbred Cows. Indian J. Animal Sciences 51: 832-833 
 
7.     Talvelkar, B. A., Raikar, R. K., Sheth, A. R. and Gadgil, B. A. (1981).Diurnal Variation in The Serum LH and Prolactin Levels in Gir and Crossbred Heifers. Indian J. Dairy Sci. 34 : 469-471
 
8.     Raikar, R. K., Joshi, V. G., Mantri, A. M., Deopurkar, V.L. and Deshmukh, B. T. (1981) A note on the effect of Prajana on layer performance. The Indian Poultry Gazette 65 (1) : 27 – 2 
 
9.     Talvelkar, B. A., Raikar, R.K. and Gadgil, B. A. (1982). Note on Serum Luteinizing Hormone and Protactin Levels in Purebred Gir and Crossbred Heifers before the Onset of Puberty. Indian J. Anim. Sci.  52 : 948-950.
 
10.  Talvelkar, B. A., Raikar, R .K.,Sheth, A. R. and Gadgil, B. A. (1982). Serum LH and Prolactin Levels during Late Pregnancy, Parturition and Early Lactation Period in Gir and Crossbred Cows. Indian J. Dairy Sci. 35 : 318 – 321. 
 
11.  Talvelkar, B. A., Raikar, R.K., Sheth, A. R. and Gadgil, B. A.(1982). Serum Prolactin Levels and Milk Yield in Gir and Crossbred Cows. Indian J. Dairy Sci. 35: 361-365
 
12.  Talvelkar, B. A., Raikar, R. K., Sheth, A. R. and Gadgil, B. A. (1982). Serum LH and Serum Prolactin Levels during Postpartum Period in Purebred Gir and Crossbred Cows.Indian J. Dairy Sci. 35:  505-510 
 
13.  Kulkarni, B A., Talvelkar, B. A., Deshmukh, B. T., Kolhatkar V. P., Patankar D. D. and Gokani, S. S. (1983). Biochemical Studies in Gir and Crossbred Dairy Cows. Indian Vet.J. 60: 17-22.
 
14.  Deshmukh, B. T. and Chorey, P. A. (1983) Influence of milking rate on yield and composition of milk. P. K. V. Research Journal7 (2) : 62 – 65 
 
15.  Kulkarni, B. A., Talvelkar, B. A., Kaushik, R. V., Gokani, S. S., Patankar, D. D., Kulkarni, B. S. (1984). Biochemical Studies in Gir and Jersey Lactating Cows. Indian Vet. J. 61 :  377 – 381.
 
16.  Kulkarni, B. A., Talvelkar, B. A., Kaushik, R. V., Gokani, S. S., Patankar, D. D. and Kulkarni, B. S. (1984). Studies on Serum Biochemical Constituents in Lactating and Dry Indian buffaloes. Indian Vet.J. 61: 564 – 568. 
 
17.  Deshmukh, B. T and Ludri, R. S. (1985) Residual milk at different frequencies of milking and stages of lactation in crossbred cows. Indian Journal of Animal Sciences. 55 (10) : 898 – 900
 
18.  Deshmukh, B. T. and Ludri, R. S. Effect of oxytocin administration at different frequencies of feeding and milking on yield and organic constituents of milk in crossbred cows. (1987) International Journal of Animal Sciences. 2 (2) : 109 – 112 
 
19.  Talvelkar, B. A. (1988). Studies on Certain Aspects of Eggs in The Purebred Strains of White Leghorn, Australorp and Their Crosses, White – Austro. I.A.L.V.  Bulletin 2 :  27 –  32.
20.       20. Deshmukh, B. T. (1989) Tin Vela DudhKadhunDudhachaAdhikUtpadan (Marathi Shetkari Magazine. March Issue PP    23 – 24
21.  22. Deshmukh, B. T. and Ludri, R. S. Citric acid in milk of crossbred cows at different frequencies of milking and stages of lactation. (1989) Indian Journal of Animal Sciences. 59 (4) : 474 – 475
22.  23. Deshmukh, B. T.  (1989)Effect of radioactive contamination on animal and public health. Dairy Guide. 12(10-12) : 25 – 27
23.  . Deshmukh, B. T. and Ludri, R. S. (1990) Some observations on water consumption and body weights in crossbred cows fed and milked at varying intervals. Indian Journal of Dairy Science. 43(2) : 160 – 163
24.  Kulkarni, B. A., Talvelkar, B. A., Kaushik, R. V., Gokani, S. S., Patankar, D. D. and  Kulkarni, B. S. (1990). Studies on Blood Metabolic Profiles in Gir, Rathi, Kankrej and Harayana Lactating Cows. J. Vety. Physiol& Allied Sci. 1 :  16 – 27.
25.  Bhangale, P. B., Joshi. V. G., Kulkarni, B. A., Talvelkar, B. A. and Deshmukh, B. T. (1990). A study of Effects of some Climatic Factors on Physiological Responses in Gir and Crossbred Lactating Cows. Indian J. Dairy Sci. 43: 282 – 286.
26.  . Deshmukh, B. T. and Ludri, R. S (1991)  Influence of equal hours of feeding and milking on secretion of milk in lactating crossbred cows. Indian Journal of Dairy Science. 44 (2) : 147 – 150
27.  . Deshmukh, B. T., Joshi, V. G. Patil, M. D. Talvelkar, B. A. and Mhatre, A. J. (1991).Induced lactation in dairy cattle for increased milk production: Effect on Major Milk Constituents.Indian J. Dairy Sci.   45 : 110-113.
28.  . Joshi, V. G., Rajwade, N. A., Desai , N. K. and Talvelkar, B. A. (1992)  .
29.  The Study of Indigenous and White Leg Horn Layers in Their Key Physiological StatesIndian J. Anim. Sci. 62 : 629-634.
30.  Patil M. D., Talvelkar, B. A., Joshi V. G. and Deshmukh, B. T., (1992).
Haematological Studies in MurrahBuffaloes.Indian Vet. J. 69 : 661 –663.
31.  Patil M. D., Talvelkar, B. A., Joshi V. G. and Deshmukh, B. T. (1992). Haematological Studies in Murrah Buffaloes: TLC, DLC and micrometry of leucocytes. Indian Vet. J. 69 :760 – 761.
32.  . Kulkarni, B. A, Talvelkar, B. A. , Kaushik, R. V., Gokani, S. S., Patankar, D. D. and Kulkarni B. S. (1993) . Studies on Blood Metabolic Profiles in Crossbred Lactating Cows.Indian J. Anim. Sci. : 63:  716 –719.
33.  . Deshmukh, B. T., Joshi, V. G., Katkam, R. R. and Puri, C. P. (1993) Hormonal induction of lactation in dairy cattle: Major milk constituents and oestradiol and progesterone levels in serum and milk. Indian Journal of Animal Sciences. 63 (6) : 611 – 617
34.  . Manzoor, M; Deshmukh, B. T., Joshi V. G., Kulkarni, B. A.,  Talvelkar, B. A., Pahuja, D. N. Borkar, A. V. and Samuel A. M. (1994 ). Concentration of some Major Elements in Blood Plasma and Milk of Crossbred Cows during Different Stages of Lactation Indian J. Dairy Sci. 47: 94 –98.
35.  . Kulkarni, B. A., Deshmukh, B. T., Katkam, R. R. and Puri, C. P. (1994) Follicular fluid steroid hormone levels of the Indian buffalo. Buffalo Journal.1 :  71 – 74
36.  . Deshmukh, B. T. and Ludri, R. S. (1994) Influence of frequency of feeding and milking on dry matter intake, milk yield and composition in crossbred cows. Indian Journal of Animal Sciences. 64 (9) : 992 – 995
37.  . Jagdale, D. S. ,Talvelkar, B. A., Mantri, A. M. and Deshmukh, B. T.(1995). Studies on Lipid Profile in Crossbred Cows Indian J. Dairy Sci. 48: 96- 98
38.  Dalvi, S. H., Deshmukh, B. T., Mantri, A. M, and Talvelkar, B. A. (1995).
Concentration of Blood Serum Thyroid Hormones during Late Pregnancy, Parturition and Early Lactation in Crossbred Cows. Indian J. Anim. Sci. : 65: 15 – 19.
39 Bansode, P. D., Mantri, A. M., Deshmukh, B. T. and Talvelkar, B. A.  (1996). Effect of Intramuscular injection of Oxytocin on Milk Production and its Constituents. Indian J. Dairy Sci. 40 : 718- 720
 
40 Deshmukh, B. T.  andLudri, R. S. (1996) Dry matter consumption and milk production of crossbred cows as influenced by the environmental variables. Indian Journal of Dairy Science. 49 (10) : 648 – 653
 
41. Jagdale, D. S. ,Talvelkar, B. A. , Mantri, A. M. and Deshmukh, B. T. (1996 – 98).Studies on Estradiol –17 ß and Progesterone in Crossbred Cows.J. Bombay Vet. Coll. 6 : 41- 43.
42. Deshmukh, B. T. and Mantri, A. M. (1997Thyroid hormones concentration during lactation in cows.Indian Journal of Animal Sciences. 67 (10) : 880 – 881 
43. Bhere, S. K., Deshmukh, B. T, Nagvekar A. S. and Talvelkar, B. A.  (1997).
Effect of Bovine Somatotropin on Production Parameters in Cows.
Indian J. Anim. Sci. : 67: 897 – 901. 
44. Deshpande, S. M., Mantri, A. M., Talvelkar, B. A. and Deshmukh, B. T. (1998).
Studies on Macroelements during Gestation and Early Postpartum Period in Gir and Crossbred Cows.Indian J. Dairy Sci. 51: 275 – 279. 
45. Garje, V. D., Talvelkar, B. A., Mantri, A. M. and Deshmukh, B. T. (1999).
Effect of Exogenous Bovine Somatotropin on Sodium, Potassium and Chloride Contents of Milk of Lactating Crossbred Cows.Indian J. Anim. Sci. 69 : 482 – 484. 
46. Ingole, S. D. Talvelkar, B. A., Deshmukh, B. T. and Nagvekar, A. S. (1999).
Serum Enzyme Profile during Gestation and Early Lactation in Gir and Crossbred Cows.Indian J. Anim. Sci. 69 : 479 – 481. 
47. Gadhave, L. R., Mantri, A. M., Talvelkar, B. A.  andDeshmukh, B. T. (2000).
Serum Protein Profile during Gestation and Early Postpartum Period in Gir and Crossbred Cows.Indian Vet. J. 77 : 114 – 116. 
48. Atak, B. V., Talvelkar, B. A. , Deshmukh, B. T., Nagvekar, A. S. and Patil, S. P. (2000) .Serum Enzyme Profile during Growth in Gir and Crossbred Calves.Indian Vet. J. 77 : 300 – 302. 
49. Patil, S. P., Talvelkar, B. A. , Deshmukh, B. T., Nagvekar, A. S. and Atak, B. V. (2000 ).Studies on Some Blood Values during Growth in Gir and Crossbred Calves.Indian Vet. J. 77 : 296 – 299. 
50. Vadnere, N. B., Deshmukh, B. T., Talvelkar, B. A., Nagvekar, A. S. and Chinchkar, S. R. (2000) Induced hypothyroidism in goats.Indian Journal of  Animal Sciences. 70 (6) : 600 – 602 
51. Harlikar, M. N., Ingole S. D. and Talvelkar, B. A. (2000).
Studies on Serum Iron and Copper levels in crossbred female calves and heifers The Veterinarian 24 : 5-6. 
52. Deshmukh, B. T. (2000)Somatotropin and lactation ISSRF Newsletter July 2005: 18 – 19 
53. Harlikar, M. N., Talvelkar, B. A., Deshmukh, B. T., Nagvekar, A. S and Ingole S.D.( 2000)Trace elements profile during growth in crossbred calves and heifers.Indian Journal of Animal Sciences. 70(11): 1147-1149 
54. Deshmukh, B. T., Nagvekar, A. S., Talvelkar, B. A., Dalvi, S.H. and Chinchkar, S.R(2001)Effect of bovine somatotropin on blood serum minerals, thyroid hormones and eproductive performance of lactating crossbred cows.Indian Journal of Animal Sciences. 71(7): 663-66 
55. Bharucha, S. V., Deshmukh, B. T., Nagvekar, A. S. and Talvelkar, B. A. (2001)
Effect of bovine somatotropin on blood serum protein profile in lactating crossbred cows.Indian Journal of Animal Sciences. 71(7): 667-669 
56. Bhide, S. V., Deshmukh, B. T., Talvelkar, B. A.  andNagvekar, A. S.(2001) Effect of induced hypothyroidism on blood biochemical constituents in goats.Indian Veterinary Journal . 78: 205-208 
57. Vadnere, N. B., Deshmukh, B. T., Talvelkar, B. A. and Nagvekar, A. S. (2002)Effect of induced hypothyroidism on haematological parameters in goats.Indian Journal of Animal Sciences. 72(2): 151-153 
58. Sonawane, N. S., Talvelkar, B. A., Nagvekar, A. S., Bharucha, S. V. and Deshmukh, B. T. (2002)Effect of recombinant bovine somatotropin on the blood lipid profile in lactating crossbred cows.Indian Journal of Animal Sciences. 72(4): 306-308 
59. Mehere, Y. S., Talvelkar, B. A., Deshmukh, B. T., Nagvekar, A. S. and Ingole, S. D. (2002)Haematological and Trace Elements Profile during Peripartum Period in crossbred Cows.Indian Journal of Animal Sciences. 72 : 148-150
60. Nalavade, S. B., Talvelkar, B. A., Deshmukh, B. T., Nagvekar, A. S., Ingole, S. D. and Vadnere, N. B. (2002).Comparative Study of Blood serum Lipid Profile in Buffalo and Cow Bulls.The Journal of Bombay Veterinary College. 10 : 15 – 18 
61. Bahiram, K. B., Talvelkar, B. A., Deshmukh, B. T., Nagvekar, A. S. and Ingole, S. D. (2002).Mineral Profile During Growth in crossbred Calves and Heifers.The Journal of Bombay Veterinary College.10 : 25 – 27 
62. Nikam, S. R., Deshmukh, B. T., Vadnere, N. B., Nagvekar, A. S and Ingole, S. D. (2005).Comparative appraisal of seminal plasma lipid profile in buffalo and cow bulls.Journal of  Bombay Veterinary College. 13 (1&2) : 46 – 49 
63. Bidye, S. V., Deshmukh, B. T., Vadnere, N. B., Nagvekar, A. S and Ingole, S. D. (2005).Comparative appraisal of serum thyroid hormones in buffalo and cow bulls.Journal of  Bombay Veterinary College. 13 (1&2) : 57 – 59 
64. Kancharla, S. B., Deshmukh, B. T., Vadnere, N. B., Nagvekar, A. S and Ingole, S. D. (2006).Comparative appraisal of seminal plasma  trace elements  in buffalo and cow bulls.Indian Journal of  Animal Sciences. 76 (2) : 137 – 138 
65. Talvelkar, B. A., Patil, R. R., Ingole, S. D., Bharucha, S. V. and Pawar, L. D. (2006)Haematological profile of buffaloes during peripartum period.Journal of  Bombay Veterinary College. 14 (1&2) : 75 – 77 
66. Talvelkar, B. A., Patil, R. R., Ingole, S. D., Bhere S. K. and Bharucha, S. V. (2006) Haematological profile of buffaloes during gestation and lactation.Journal of  Bombay Veterinary College. 14 (1&2) : 93 – 95 
67. Talvelkar, B. A., Patil, R. R., Ingole, S. D. and Bharucha, S. V. (2007)Influence of enzymes on milk production and reproductive efficiency.IntasPolivet. 8(1) :185 – 187 
68. Dhaware, S. D., Deshmukh, B. T., Nagvekar, A. S., Ingole, S. D., Dalvi, S. H and Shiny Joy. (2007)Biochemical profile of buffalo follicular fluid.Buffalo Journal.1 : 19 – 28 
69. Talvelkar, B. A., Patil, R. R., Ingole, S. D. and Bharucha, S. V. (2008)Serum enzymatic profile of buffaloes during gestation, lactation.andperipartumperiod.Indian Journal of  Animal Sciences. 78 (3) : 247 – 250. 
72. Nagvekar, A. S., Deshmukh, B. T and Ingole, S. D (2012)Profiles of serum somatotropin, gonadotropins, ovarian steroids and thyroidal hormones during gestation of Murrah buffalo.Indian Vet. J. 
 


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