Livestock Product Technology - Academics

With adoption of the curriculum of Veterinary Council of India for under-graduate teaching by the MAFSU.

Academic

Academic Regulations:

Admissions:

Sr. No.	Name of Student	Enrl. No.	Email Address	Name of Advisor

Course offered :: UG, PG , PhD - Semester / Year wise

Sr. No.	Course No	Title	Credit	Course offered in the Year

Sr No	Course No.	Title	Credit	Semester

Lecture schedule UG

MAHARASTRA ANIMAL & FISHERY SCIENCES UNIVERSITY, NAGPUR.
NAME OF DISCIPLINE	VETERINARY PHARMACOLOGY AND TOXICOLOGY
PROFESSIONAL YEAR	III
CREDIT HOURS	4 + 1 = 5
BOS APPROVAL RESOLUTION NO.

Sr. No.	Unit No.	Lecture No.	Topic to be Covered
1	Unit 1	1	Introduction to Veterinary Pharmacology, Historical development of Pharmacology.
2	Unit 1	2	Branches of Pharmacology and scope of Pharmacology.
3	Unit 5	3	Introduction to Chemotherapy, Classification
4	Unit 5	4	General principles in antibacterial chemotherapy (definition of antibiotic, MBC, MIC, and classification of antibiotics with examples, etc.)
5	Unit 1	5	Pharmacological terms and definitions.
6	Unit 1	6	Sources and nature of drugs
7	Unit 5	7	Antibacterial resistance
8	Unit 5	8	Rational use of Chemotherapeutic agents.
9	Unit 1	9	Drug Discovery & Drug development
10	Unit 1	10	Bio Prospecting of Drugs
11	Unit 5	11	Sulphonamides, mechanism of action, spectrum, clinical uses, toxicity, dose and route of administration, and their combination with diaminopyrimidines
12	Unit 5	12	Other antimicrobial compounds like Sulfones, Nitrofurans, Nalidixic acid.
13	Unit 1	13	Principles of drug activity: Pharmacokinetics – Routes of drug Administration.
14	Unit 1	14	Absorption of Drugs.
15	Unit 5	15	Quinolones and Fluoroquinolones (structure, mechanism, spectrum, clinical uses, toxicity, dose and route of administration).
16	Unit 5	16	Penicillin – Penicillin, synthetic penicillin, beta-lactamase inhibitors.
17	Unit 1	17	Distribution of Drug.
18	Unit 1	18	Biotransformation of drugs & species variation in Biotransformation.
19	Unit 5	19	Combination of Penicillin with other drugs.
20	Unit 5	20	Cephalosporin and Cephamycins.
21	Unit 1	21	Excretion of drugs.
22	Unit 1	22	Pharmacodynamics and concept of drug and receptor, types of receptor.
23	Unit 5	23	Aminoglycoside –I: Gentamicin, Streptomycin.
24	Unit 5	24	Aminoglycoside –II: Neomycin, Kanamycin, Amikacin, etc.
25	Unit 1	25	Dose-response relationship.
26	Unit 1	26	Terms related to drug activity and drug interaction.
27	Unit 5	27	Tetracycline and tetracycline derivatives.
28	Unit 5	28	Amphenicols (Chloramphenicol, thiamphenicol, florphenicol).
29	Unit 1	29	Factors modifying the drug effect.
30	Unit 1	30	Fundamentals of drug-screening & Drug delivery systems.
31	Unit 5	31	Macrolide antibiotics.
32	Unit 5	32	Lincosamides.
33	Unit 1	33	Adverse drug reactions.
34	Unit 1	34	Introduction to biopharmaceutics and gene therapy.

35	Unit 5	35	Polypeptides (Polymixins, Bacitracin)
36	Unit 5	36	Glycopeptide antibiotics.
37	Unit 2	37	Introduction to Autonomic Nervous System
38	Unit 2	38	Autonomic relationship, central integration
39	Unit 5	39	Miscellaneous agents: Novobiocin, virginiamycin, tiamulin.
40	Unit 5	40	Antitubercular drugs.
41	Unit 2	41	Neurohumoral transmission.
42	Unit 2	42	Adreno receptors agonists, their SAR.
30% course completion. FIRST INTERNAL ASSESSMENT EXAM.
43	Unit 5	43	Antifungal agents: Topical and systemic agents.
44	Unit 5	44	Antifungal agent: antibiotics.
45	Unit 2	45	Adreno receptor antagonists & adrenergic neuron blockers.
46	Unit 2	46	Cholinergic receptors agonists.
47	Unit 5	47	Anthelmintics: introduction, classification, ideal Anthelmintics.
48	Unit 5	48	Anthelmintic Resistance.
49	Unit 2	49	Cholinergic receptors antagonists.
50	Unit 2	50	Ganglionic stimulants and blockers.
51	Unit 2	51	Autacoids I: Histamine and antihistamine agents.
52	Unit 5	52	Mechanism of action of Anthelmintics, Antinematodal drugs.
53	Unit 5	53	Anticestodal and antitrematodal drugs and broad-spectrum Anthelmintics-I.
54	Unit 2	54	Autacoids II: 5 – Hydroxytryptamine and its antagonists.
55	Unit 2	55	Anticestodal and antitrematodal drugs and broad-spectrum Anthelmintics-II.
56	Unit 5	56	Antiprotozoan drugs I – for Trypanosomiasis, Babesiosis and Anaplasmosis.
57	Unit 2	57	Autacoids III: Prostaglandins, Angiotensin and Bradykinin.
58	Unit 3	58	Drugs acting on central nervous system (CNS): Introduction and Classification.
59	Unit 5	59	Antiprotozoan drugs II – Giardiasis, Trichomoniasis and Amoebiasis.
60	Unit 5	60	Anticoccidial drugs- general principles, classification, and mechanism of action and dosage of Anticoccidial drugs.
61	Unit 3	61	History of general anaesthetics and theories of anaesthesia.
62	Unit 3	62	Pharmacology of neurotransmitters of CNS.
63	Unit 5	63	Ectoparasiticides I.
64	Unit 5	64	Ectoparasiticides II.
65	Unit 3	65	Inhalant anaesthetics I: Ether, Halothane, and Nitrous Oxide.
66	Unit 3	66	Inhalant anaesthetics II: Enflurane, Isoflurane, Methoxyflurane, Cyclopropane, Sevoflurane & recent development.
67	Unit 5	67	Antiviral drugs.
68	Unit 5	68	Anticancer drugs.
69	Unit 3	69	Intravenous Anaesthesia – Barbiturates its Classification and SAR.
70	Unit 3	70	Barbiturates- Pharmacological Action and Uses.
71	Unit 5	71	Antiseptics and disinfectants –I.
72	Unit 5	72	Antiseptics and disinfectants –II.
73	Unit 3	73	Dissociative anaesthetics – Ketamine, Phencyclidine etc.
74	Unit 3	74	Hypnotics and sedatives.
75	Unit 5	75	Growth promoters.
76	Unit 5	76	Pharmacology of indigenous medicinal plants: Scientific name, common name, active principles, pharmacological actions and therapeutic uses of Ginger, Ocimum, Neem, Piper longum, Withania, Leptadenia, Tinospora, Embilica.
77	Unit 3	77	Tranquilizers.
78	Unit 3	78	Psychotropic drugs – classification and mechanism.

79	Unit 5	79	Pharmacology of indigenous medicinal plants: Scientific name, common name, active principles, pharmacological actions and therapeutic uses of Eucalyptus, Glycerrhiza, Trichospermum, Curcuma, Adhantoda, Butea, Aloes, Sena, Rheubarb, Catechu etc.
80	Unit 6	80	General Toxicology: Definitions, History of toxicology.
81	Unit 3	81	Anticonvulsants: Phentobarbitone sodium, Phenytoin sodium, Primidone, etc.
82	Unit 3	82	Analgesics: Opioid analgesics, Morphine and derivatives.
83	Unit 6	83	Fundamentals and scope of Toxicology.
84	Unit 6	84	Sources and classification of toxicants.
85	Unit 3	85	Non-narcotic analgesics, salicylates, Para-aminophenol derivatives, Pyrazolone derivatives.
86	Unit 3	86	Non-steroidal anti-inflammatory drugs (NSAID), COX-I and COX-II Inhibitors.
60% course completion. SECOND INTERNAL ASSESSMENT EXAM.
87	Unit 6	87	Factors modifying toxicity.
88	Unit 6	88	General approaches of diagnosis of poisoning.
89	Unit 3	89	Analeptics & CNS stimulants.
90	Unit 3	90	Drugs acting on somatic nervous system: Local anaesthetics.
91	Unit 6	91	General approaches for treatment of poisoning.
92	Unit 6	92	Toxicity caused by lead.
93	Unit 3	93	Central muscle relaxants.
94	Unit 3	94	Peripheral muscle relaxants.
95	Unit 6	95	Toxicity caused by Arsenic.
96	Unit 6	96	Toxicity caused by Mercury.
97	Unit 3	97	Euthanasia.
98	Unit 4	98	Drugs acting on digestive system: emetics, antiemetics, purgatives, and antidiarrhoeals.
99	Unit 6	99	Toxicity caused by Copper & Molybdenum.
100	Unit 6	100	Toxicity caused by Selenium and Selenium-accumulating plants.
101	Unit 4	101	Drugs acting on digestive system: Stomachic, antacids, antiulcer, and prokinetics.
102	Unit 4	102	Drugs acting on digestive system: Carminatives, antizymotics, cholerectics & cholagogues.
103	Unit 6	103	Toxicity caused by Nitrate and Nitrites.
104	Unit 6	104	Toxicity caused by Chlorate, common salt, and urea.
105	Unit 4	105	Rumen pharmacology, metabolic diseases of ruminal & its treatment.
106	Unit 4	106	Drugs acting on Cardiovascular system: cardiac glycosides.
107	Unit 6	107	Toxicity caused by Phosphorus, Iodine & Fluorine.
108	Unit 6	108	Poisonous Plants: Cyanogenetic Plants, Oleander, and Cotton.
109	Unit 4	109	Antiarrhythmic drugs - quinidine, procainamide, calcium channel blockers.
110	Unit 4	110	Pharmacology of Vasodilators.
111	Unit 6	111	Poisonous plants: oxalate-producing plants.
112	Unit 6	112	Plants causing Thiamine deficiency.
113	Unit 4	113	Antihypertensive drugs.
114	Unit 4	114	Coagulants, anticoagulants (local and systemic), and haematinics.
115	Unit 6	115	Poisonous plants: Abrus, Ipomoea, Datura, Nux Vomica, Castor, etc.
116	Unit 6	116	Plants causing photosensitization and lathyrism.
117	Unit 4	117	Drugs acting on respiratory system: Expectorants, antitussives, and respiratory stimulants.
118	Unit 4	118	Bronchodilators and mucolytics.
119	Unit 6	119	Toxicity caused by Agrochemicals I: Insecticides - Chlorinated hydrocarbons, Organophosphates.
120	Unit 6	120	Toxicity caused by Agrochemicals II: Carbamates, Pyrethroids, newer insecticides.

121	Unit 4	121	Drugs acting on urogenital system: Diuretics, their classification, and mechanisms of action.
122	Unit 4	122	Urinary alkalizers and acidifiers.
123	Unit 6	123	Toxicity caused by Agrochemicals III: Herbicides.
124	Unit 6	124	Toxicity caused by fungicides.
125	Unit 4	125	Fluid therapy.
126	Unit 4	126	Ecbolics and tocolytics.
127	Unit 6	127	Toxicity caused by rodenticides.
128	Unit 6	128	Fungal toxins: Aflatoxins, Rubratoxin, Ochratoxin.
129	Unit 4	129	Drugs acting on skin and mucous membranes: Emollients, demulcents, and counter irritants.
90% course completion. THIRD INTERNAL ASSESSMENT EXAM.
130	Unit 4	130	Immuno modulators & Bioenhancers.
131	Unit 6	131	Fungal toxins: Sporidesmin, Citrinin, F – 2 toxin, Trichothecenes, Ergot & Fescue.
132	Unit 6	132	Bacterial toxins: Botulinum toxin and tetanus toxin.
133	Unit 4	133	Pharmacotherapeutics of Pituitary Hormones – I.
134	Unit 4	134	Pharmacotherapeutics of Gonadal Hormones.
135	Unit 6	135	Venomous bites and stings: Snake, scorpion, spider.
136	Unit 6	136	Venomous bites and stings: bees and wasp, toad and fishes (puffer fish, shellfish).
137	Unit 4	137	Pharmacotherapeutics of adrenal Hormones.
138	Unit 4	138	Pharmacotherapeutics of Pancreatic Hormones – II.
139	Unit 6	139	Toxicity caused by food additives and preservatives.
140	Unit 6	140	Drug & drug residual toxicology.
141	Unit 4	141	Drug used for abuse in Veterinary field.
142	Unit 6	142	Environmental pollutants: Air and water pollutants, Methane pollution, acid rain, Green house effect-I.
143	Unit 6	143	Environmental pollutants: Air and water pollutants, Methane pollution, acid rain, Green house effect-II.
144	Unit 6	144	Concept of radiation hazards.

Modification as per suggestions from BOS

Lecture schedule PG

Course Title : Concepts of Pharmacology, Drug Design and Development Course Code : VPT 601 Credit Hours : 2+0
Sr. No	Name of the topic
1	Scope of pharmacology, nature and sources of drugs and other therapeutic agents
2	Concept of Pharmacology in Therapeutics
3	Scope of pharmacology, nature and sources of drugs and other therapeutic agents
4	Principles of biopharmaceutics and dosage forms of drugs
5	Principles of biopharmaceutics and dosage forms of drugs
6	Routes of Drug Administrations
7	Principles of Pharmacokinetics-Absorption, distribution, metabolism and excretion of drugs
8	Principles of Pharmacokinetics-Absorption, distribution, metabolism and excretion of drugs
9	Principles of Pharmacokinetics-Absorption, distribution, metabolism and excretion of drugs
10	Principles of Pharmacokinetics-Absorption, distribution, metabolism and excretion of drugs
11	Principles of Pharmacokinetics-Absorption, distribution, metabolism and excretion of drugs
12	Application of Pharmacokinetics
13	Principles of drug action, rational, empirical and various other therapeutics
14	Principles of drug action, rational, empirical and various other therapeutics
15	Pharmacodynamics-targets for drug actions (enzymes, ion channels, structural and transporter proteins)
16	Pharmacodynamics-targets for drug actions (enzymes, ion channels, structural and transporter proteins)
17	Pharmacodynamics-targets for drug actions (enzymes, ion channels, structural and transporter proteins)
18	Pharmacodynamics-targets for drug actions (enzymes, ion channels, structural and transporter proteins)
19	Receptor mediated drug action, types of drug receptors, second messengers of drug action and signal transduction
20	Receptor mediated drug action, types of drug receptors, second messengers of drug action and signal transduction
21	Receptor mediated drug action, types of drug receptors, second messengers of drug action and signal transduction
22	Receptor mediated drug action, types of drug receptors, second messengers of drug action and signal transduction
23	Regulation and malfunctioning of diseases
24	Quantitation of drug-receptor interactions and elicited effects
25	Quantitation of drug-receptor interactions and elicited effects
26	Drug interactions and adverse drug reactions
27	Drug interactions and adverse drug reactions
28	Drugs design and development, Screening and drug assay
29	Drugs design and development, Screening and drug assay
30	Drugs design and development, Screening and drug assay
31	Clinical drug trials
32	Clinical drug trials
33	Drug safety, drug standards and regulations
34	Drug safety, drug standards and regulations
35	Gene therapy and novel drug delivery systems
36	Gene therapy and novel drug delivery systems

I. Course Title : Autonomic and Autacoid Pharmacology II. Course Code : VPT 602 III. Credit Hours : 2 + 1
Sr. No	Name of the topic
1	Introduction to autonomic nervous system (ANS), Anatomical and physiological considerations of autonomic and somatic motor nervous system
2	Introduction to autonomic nervous system (ANS), Anatomical and physiological considerations of autonomic and somatic motor nervous system
3	Introduction to autonomic nervous system (ANS), Anatomical and physiological considerations of autonomic and somatic motor nervous system
4	Neurohumoral transmission
5	Neurohumoral transmission
6	Exceptions to generalization of ANS, Agents modulating peripheral nervous system, non-adrenergic-non-cholinergic (NANC) transmission
7	Exceptions to generalization of ANS, Agents modulating peripheral nervous system, non-adrenergic-non-cholinergic (NANC) transmission
8	Exceptions to generalization of ANS, Agents modulating peripheral nervous system, non-adrenergic-non-cholinergic (NANC) transmission
9	Sympathetic nervous system, adrenergic agonists, antagonists and adrenergic neuron blockers
10	Sympathetic nervous system, adrenergic agonists, antagonists and adrenergic neuron blockers
11	Sympathetic nervous system, adrenergic agonists, antagonists and adrenergic neuron blockers
12	Sympathetic nervous system, adrenergic agonists, antagonists and adrenergic neuron blockers
13	Therapeutic uses of sympathetic drugs and blockers
14	Parasympathetic nervous system, cholinergic agonists, antagonists and cholinergic neuron blockers
15	Parasympathetic nervous system, cholinergic agonists, antagonists and cholinergic neuron blockers
16	Parasympathetic nervous system, cholinergic agonists, antagonists and cholinergic neuron blockers
17	Parasympathetic nervous system, cholinergic agonists, antagonists and cholinergic neuron blockers
18	Therapeutic uses of parasympathetic drugs and blockers
19	Ganglion stimulating and blocking drugs
20	Ganglion stimulating and blocking drugs
21	Neuromuscular blocking drugs
22	Introduction to immunity and inflammation
23	Introduction to immunity and inflammation
24	Immunostimulants, immunosuppressants and tolerogens
25	Histaminergic and antihistaminics
26	Histaminergic and antihistaminics
27	Serotonin and antiserotonin agents
28	Serotonin and antiserotonin agents
29	Kinins as mediators of inflammation
30	Kinins as mediators of inflammation
31	Eicosanoids and platelet activating factor
32	Eicosanoids and platelet activating factor
33	Eicosanoids and platelet activating factor
34	Angiotensins and other putative autacoids
35	Angiotensins and other putative autacoids
36	Angiotensins and inhibitors of renin-angiotensin system

PRACTICAL

Sr. No	Name of the topic
1	Demonstration of adrenergic activity on isolated heart
2	Demonstration of cholinergic activity on isolated intestine
3	Demonstration of adrenergic / cholinergic activity on rabbit eye
4	Demonstration of adrenergic / antiadrenergic activity on blood pressure
5	Effect of drugs on guinea pig tracheal chain preparation
6	Demonstration of effects of drugs on isolated guinea pig ileum
7	Effects of drugs on rabbit jejunum
8	Demonstration of adrenergic activity on isolated rat uterus
9	Demonstration of cholinergic drugs on isolated abdominal muscle
10	Demonstration of the effect of drugs on ECG
11	Effects of autonomic drugs on blood pressure, ECG, etc.
12	Effects of autonomic drugs on blood pressure, ECG, etc.
13	Effect of autacoids on different systems-Isolated Intestine
14	Effect of autacoids on different systems-Isolated Intestine
15	Effect of autacoids on different systems-Isolated Lungs
16	Effect of autacoids on different systems-Isolated Lungs
17	Effect of autacoids on different systems-Isolated Uterus
18	Effect of autacoids on different systems-Isolated Uterus

Course Title : CNS Pharmacology Course Code : VPT 603 Credit Hours : 2 +1
Sr. No	Name of the topic
1	Introduction to CNS – Physiological and anatomical considerations
2	Drugs action on CNS
3	Drugs action on CNS
4	Central neurotransmitters
5	Central neurotransmitters
6	General anaesthesia – History, theories and stages of general anaesthesia
7	General anaesthesia – History, theories and stages of general anaesthesia
8	General anaesthesia – History, theories and stages of general anaesthesia
9	Adjuvants to general anaesthetics
10	Inhalant general anaesthetics
11	Inhalant general anaesthetics
12	Inhalant general anaesthetics
13	Injectable general anaesthetics
14	Injectable general anaesthetics
15	Injectable general anaesthetics
16	Local anaesthetics
17	Local anaesthetics
18	Hypnotics and sedatives
19	Hypnotics and sedatives
20	Hypnotics and sedatives
21	Psychotropic drugs and drugs modifying abnormal behavior of animals
22	Psychotropic drugs and drugs modifying abnormal behavior of animals
23	Anticonvulsants
24	Anticonvulsants
25	Opioid agonists (analgesics) and antagonists
26	Opioid agonists (analgesics) and antagonists
27	Opioid agonists (analgesics) and antagonists
28	Non steroidal anti-inflammatory drugs (NSAIDs)
29	Non steroidal anti-inflammatory drugs (NSAIDs)
30	Non steroidal anti-inflammatory drugs (NSAIDs)
31	CNS stimulants
32	Central muscle relaxants
33	Drugs of abuse
34	Drugs of abuse
35	Current topics/Discussion on library assignments
36	Current topics/Discussion on library assignments

Practical No.	Name of the topic
1	Study on general anaesthetics – gaseous & liquid anesthesia
2	Study on general anaesthetics – gaseous & liquid anesthesia
3	Study on local anaesthetics
4	Study on local anaesthetics
5	Study on sedatives and hypnotics
6	Study on sedatives and hypnotics
7	Study on anticonvulsants
8	Study on anticonvulsants
9	Study on antipyretics
10	Study on analgesics
11	Study on analgesics
12	Study on anti-inflammatory drugs
13	Study on anti-inflammatory drugs
14	Study on psychotropic drugs
15	Study on psychotropic drugs
16	Study on CNS stimulants
17	Study on central muscle relaxants
18	Study on central muscle relaxants

Course Title : Digestive and Respiratory Pharmacology Course Code : VPT 604 Credit Hours : 2 + 1
Sr. No	Name of the topic
1	Drugs acting on Digestive System-General consideration
2	Drugs affecting salivary secretions – Sialics and antisialics
3	Drugs affecting gastric secretion – Stomachics, histamine and gastrin analogues
4	Gastric antisecretory and antiulcer drugs – H₂-receptor antagonists and proton pump inhibitors
5	Gastric antisecretory and antiulcer drugs – H₂-receptor antagonists and proton pump inhibitors
6	Antacids
7	Emetics
8	Antiemetics
9	Carminatives and antizymotics
10	Appetizers and digestants
11	Appetizers and digestants
12	Appetizers and digestants
13	Pro-kinetics
14	Pro-kinetics
15	Cathartics
16	Cathartics
17	Antidiarrhoeic drugs
18	Antidiarrhoeic drugs
19	Antidiarrhoeic drugs
20	Hepatoprotectants
21	Choleretics & Cholagogues
22	Rumen Pharmacology
23	Rumen Pharmacology
24	Rumen Pharmacology
25	Metabolic Diseases of Ruminants & its Treatments
26	Metabolic Diseases of Ruminants & its Treatments
27	Drugs Acting on Respiratory System
28	Antitussives
29	Expectorants
30	Analeptics
31	Analeptics
32	Bronchodilators and other drugs acting on respiratory system
33	Bronchodilators and other drugs acting on respiratory system
34	Gastro-esophageal reflux disease
35	Current topics/ Discussion on digestive systems
36	Current topics/ Discussion on respiratory

Practical No.	Name of the topic
1	Demonstration of anti-ulcer agents
2	Demonstration of anti-ulcer agents
3	Demonstration of effect of anti-Secretory agents
4	Demonstration of effect of anti-Secretory agents
5	Demonstration of effect of drugs on Intestinal motility
6	Measurement of intragastric pressure in rats
7	In vitro evaluation of antacid of test Compounds
8	Evaluation of antidiarrhoeal effect of Drugs
9	Demonstration of effect of anti-emetic Drugs
10	Demonstration of spasmolytic activity in isolated guinea pig lung strips
11	Demonstration of spasmolytic activity in isolated guinea pig lung strips
12	Demonstration of bronchial Hyperreactivity
13	Demonstration of spasmolytic activity in isolated trachea of g. Pig
14	Demonstration of spasmolytic activity in isolated trachea of g. Pig
15	Demonstration of effects of respiratory Depressants in conscious rats
16	Demonstration of effects of respiratory Depressants in conscious rats
17	Antitussive activity after irritant Inhalation in guinea pigs
18	Demonstration of cough induced by Mechanical stimulation

Course Title : Cardiovascular and Urinary System Pharmacology Course Code : VPT 605 Credit Hours : 2 + 0
Sr. No	Name of the topic
1	General considerations to cardiovascular system
2	General considerations to cardiovascular system
3	Myocardial stimulants – Cardiac glycosides and other myocardial stimulants
4	Myocardial stimulants – Cardiac glycosides and other myocardial stimulants
5	Myocardial stimulants – Cardiac glycosides and other myocardial stimulants
6	Anti-arrhythmic drugs
7	Anti-arrhythmic drugs
8	Anti-arrhythmic drugs
9	Vasodilators and antianginal drugs
10	Vasodilators and antianginal drugs
11	Antihypertensive agents
12	Antihyperlipidemic and anti-hypotensive drugs
13	Haemostatics and coagulants
14	Haemostatics and coagulants
15	Anti-coagulants
16	Anti-coagulants
17	Fibrinolytic and anti-platelet drugs
18	Heamtaopoietic drugs
19	Heamtaopoietic drugs
20	Blood components and blood substitutes
21	Plasma expanders
22	Drugs used in treatment of shock
23	Drugs used in treatment of shock
24	Antihyperlipoproteinemics
25	Physiological basis of renal pharmacology
26	Physiological basis of renal pharmacology
27	Diuretics
28	Diuretics and antidiuretics
29	Urinary acidifier and alkalyzers
30	Drugs affecting fluid, electrolyte and acid-base balance
31	Drugs affecting fluid, electrolyte and acid-base balance
32	Drugs affecting urinary pH and tubular transport
33	Drugs affecting urinary pH and tubular transport
34	Urinary antiseptics, uricoseric and anti-gout drugs
35	Current topics/ Discussion on library assignments
36	Current topics/ Discussion on library assignments

Course Title : Endocrine and Reproductive Pharmacology Course Code : VPT 606 Credit Hours : 2 + 1
Sr. No	Name of the topic
1	General considerations to Endocrine and reproductive systems
2	General considerations to Endocrine and reproductive systems
3	Pharmacology of drugs affecting endocrine functions of hypoteleamus
4	Pharmacology of drugs affecting endocrine functions of Pituitary gland
5	Pharmacology of drugs affecting endocrine functions of Pituitary gland
6	Pharmacology of drugs affecting endocrine functions of Pituitary gland
7	Pharmacology of drugs affecting endocrine functions of thyroid gland
8	Pharmacology of drugs affecting endocrine functions of thyroid gland
9	Pharmacology of drugs affecting endocrine functions of adrenals
10	Pharmacology of drugs affecting endocrine functions of adrenals
11	Pharmacology of drugs affecting endocrine functions of adrenals
12	Pharmacology of drugs affecting endocrine functions of the Pancreas
13	Pharmacology of drugs affecting endocrine functions of the Pancreas
14	Physiological basis of calcium and phosphorus homeostasis
15	Physiological basis of calcium and phosphorus homeostasis
16	Hormonal regulation of calcium and phosphorus homeostasis.
17	Hormonal regulation of calcium and phosphorus homeostasis
18	Pharmacology of drugs affecting male reproductive organs
19	Pharmacology of drugs affecting male reproductive organs
20	Drugs affecting spermatogenesis
21	Drugs affecting spermatogenesis and erectile dysfunctions
22	Pharmacology of drugs affecting female reproductive organs
23	Pharmacology of drugs affecting female reproductive organs
24	Drugs affecting ovulation
25	Drugs affecting ovulation
26	Drugs affecting oestrus
27	Drugs affecting conception
28	Drugs affecting conception
29	Drugs affecting gestation
30	Drugs affecting gestation
31	Drugs affecting lactation
32	Drugs affecting lactation
33	Oxytocis and other drugs affecting uterus
34	Current topics/ Disccusion on library assignments
35	Current topics/ Disccusion on library assignments
36	Current topics/ Disccusion on library assignments

Practical No.	Name of the topic
1	Demonstration of Adrenalectomy in Rats
2	Study on Glucocorticoid Activity
3	Transactivation assay for glucocorticoids
4	Biological assay of PMSG in immature female rats
5	Receptor binding assay for LH
6	Assay of long-acting thyroid stimulating factor (LATS) in mice
7	Determination of Oxytocin activity using Isolated uterus
8	Effect of Oxytocin on Chicken blood pressure
9	Estimation of oxytocin using Milk ejection in the lactating rabbit or rat
10	Oxytocin receptor determination
11	Inhibition of gonadotropin secretion in intact animals
12	Inhibition of ovulation and luteinization
13	Radioimmunoassay of rat prolactin
14	Estimation of the effect of prolactin by using the Pigeon crop method
15	Evaluation of effects of prolactin on Lactation in rabbits
16	Bioassay of Vasopressin
17	Bioassay of Acth
18	Bioassay of D-Tubocurarine

Course Title : Chemotherapy Course Code : VPT 607 Credit Hours : 2 + 1
Sr. No	Name of the topic
1	General Consideration of chemotherapy
2	Classification of antimicrobial agents, General principles of antibacterial therapy
3	Combinations of antimicrobial agents-guidelines and indications
4	Bacterial resistance and Cross resistance
5	Guidelines for successful antimicrobial therapy and Adverse reactions to antimicrobial agents
6	Sulfonamides classification, SAR, mechanism of action and antimicrobial spectrum
7	Sulfonamides and Potentiated Sulphonamides -Clinical use and adverse effects
8	Beta-Lactam antibiotics- properties, SAR and mechanism of action
9	Penicillins classification, antimicrobial spectrum and adverse effects
10	Narrow spectrum, broad spectrum and extended spectrum penicillins and their clinical use
11	Cephalosporins-classification and clinical use
12	Cephalosporins - Newer agents and their antimicrobial spectrum and clinical use
13	Beta-lactamase inhibitors
14	Aminoglycosides –properties, classification and mechanism of action
15	Aminoglycosides and Aminocyclitols- antimicrobial spectrum, resistance, clinical use and adverse effects
16	Chloramphenicol and Thiamphenicol- mechanism of action, antimicrobial spectrum, resistance, clinical use and adverse effects
17	Tetracyclines- mechanism of action, antimicrobial spectrum, resistance, clinical use and adverse effects
18	Tetracyclines Long acting - properties, pharmacokinetics, clinical use and adverse effects
19	Macrolide and licosamides antibiotics - properties, classification, antimicrobial spectrum and mechanism of action
20	Macrolides and licosamides- clinical use and adverse effects
21	Quinolones – properties, classification, antimicrobial spectrum and mechanism of action
22	Quinolones – clinical use and adverse effects
23	Anti-tubercular drugs- mechanism of action, antimicrobial spectrum, resistance, clinical use and adverse effects
24	Other antimicrobials of therapeutic importance
25	Antifungal agents- properties, classification
26	Antifungal agents-Topical and systemic drugs, clinical use and adverse effects
27	Antiviral agents- properties, classification
28	Antiviral agents- clinical use and adverse effects
29	Anticancer agents – General principles, properties, classification and mechanism
30	Anticancer agents – clinical use and adverse effects
31	Anthelmintics – General principles, properties and classification
32	Anthelmintics –Antinematodal, Anticestodal drugs
33	Anthelmintics –Antitrematodal drugs, Ectoparasiticides
34	Antiprotozoan Drugs- General principles, properties and classification
35	Antiprotozoan Drugs- clinical use in small and large animals and adverse effects
36	Anticoccidial drugs

Practical No.	Name of the topic
1	General methods for assay of chemotherapeutic agents-Disc diffusion method
2	General methods for assay of chemotherapeutic agents-Disc diffusion method
3	General methods for assay of chemotherapeutic agents-Tube dilution method and Test for bactericidal activity
4	General methods for assay of chemotherapeutic agents-Tube dilution method and Test for bactericidal activity
5	Estimation of sulfonamides in biological fluids
6	Estimation of sulfonamides in biological fluids
7	Estimation of penicillins and cephalosporins in biological fluids
8	Estimation of penicillins and cephalosporins in biological fluids
9	Estimation of penicillins and cephalosporins in biological fluids
10	Estimation of penicillins and cephalosporins in biological fluids
11	Estimation of oxytetracyclines in biological fluids
12	Estimation of oxytetracyclines in biological fluids
13	Estimation of trimethoprim in biological fluids
14	Estimation of trimethoprim in biological fluids
15	Estimation of nitrofurans in biological fluids
16	Estimation of trimethoprim in biological fluids
17	Estimation of nitrofurans in biological fluids
18	Estimation of nitrofurans in biological fluids

Course Title : Toxicology of Xenobiotics Course Code : VPT-608 Credit Hours : 2 + 1
Sr. No	Name of the topic
1	Introduction, definitions and fields of toxicology
2	History and scope of toxicology
3	Sources and classification of toxicants
4	General modes of action of poisons
5	Detoxification of poisons
6	Detoxification of poisons
7	Principles and fundamentals of toxicology
8	Principles and fundamentals of toxicology
9	Principles and fundamentals of toxicology
10	Factors affecting toxicity
11	Diagnosis of poisoning
12	Diagnosis of poisoning
13	Treatment and management of poisonings
14	Treatment and management of poisonings
15	Toxicology of metals – Arsenic
16	Toxicology of metals – Mercury
17	Toxicology of metals – Lead
18	Toxicology of metals – Copper and Molybdenum
19	Toxicology of metals – Cadmium and Iron
20	Toxicology of agrochemicals – Insecticides
21	Toxicology of agrochemicals – Herbicides
22	Toxicology of agrochemicals – Fungicides
23	Toxicology of agrochemicals – Rodenticides
24	Toxicology of agrochemicals – Rodenticides
25	Toxicology of solvents and vapours
26	Toxicology of solvents and vapours
27	Feed additives – Growth and performance enhancers, non-protein nitrogen compounds, common salt
28	Feed additives – Growth and performance enhancers, non-protein nitrogen compounds, common salt
29	Radiations and radioactive chemicals
30	Radiations and radioactive chemicals
31	Genetic and developmental toxicology
32	Genetic and developmental toxicology
33	Regulatory and forensic toxicology
34	Regulatory and forensic toxicology
35	Current topics/ Discussion of library assignments
36	Current topics/ Discussion of library assignments

Practical No.	Name of the topic
1	Collection of Material for Toxicological Investigation
2	Identification and detection of common poison
3	Extraction and separation of samples of poison from toxicological specimen
4	Dispatch and Processing of Samples for Toxicological Investigation
5	Demonstration of organophosphate toxicity and its antidotal treatment in laboratory animals
6	Demonstration of organochlorine toxicity and its antidotal treatment in laboratory animals
7	Demonstration of nitrate/ nitrites toxicity and its antidotal treatment in laboratory animals
8	Spot test for detection of heavy metals
9	Immunotoxicity study of xenobiotics/ toxicants in rats
10	Genotoxicity testing for xenobiotics by Micronuclei assay in rodents
11	Genotoxicity testing of xenobiotics by chromosomal aberrations test in rodents
12	Genotoxicity testing of xenobiotics by comet assay in rodents
13	Acute Dermal (Irritation/Corrosion) toxicity test in rabbit
14	Eye Irritation/Corrosion test in rabbit
15	Acute Oral Toxicity - Fixed Dose Procedure
16	Sub-acute toxicity study: Repeated Dose 28-day Oral Toxicity Study in Rodents
17	Sub-acute toxicity study: Repeated Dose 28-day dermal Toxicity Study in Rodents
18	Chronic toxicity study

Course Title : Toxinology Course Code : VPT 609 Credit Hours : 2 + 1
Sr. No	Name of the topic
1	Introduction to plant toxicology, toxins, venoms, mycotoxins, bacterial toxins and phytotoxins etc.
2	Classification and identification of chemical constituents of poisonous plants
3	Classification of Toxins (Phytotoxins, Microbial toxins)
4	Phytotoxins their sources and effects
5	Phytotoxins their sources and effects
6	Study of toxicity of Nitrate/nitrite containing plants: sources, mechanism of toxicity, clinical findings, diagnosis, treatment and control
7	Study of toxicity of Nitrate/nitrite containing plants: sources, mechanism of toxicity, clinical findings, diagnosis, treatment and control
8	Study of toxicity of cyanide containing plants: sources, mechanism of toxicity, clinical findings, diagnosis, treatment and control
9	Study of toxicity of cyanide containing plants: sources, mechanism of toxicity, clinical findings, diagnosis, treatment and control
10	Study of plants containing lectins and cardiac glycosides
11	Photosensitization – I: mechanism of toxicity, clinical signs and treatment
12	Photosensitization – II: mechanism of toxicity, clinical signs and treatment
13	Bracken fern poisoning – Clinical signs, diagnosis and treatment
14	Toxicity of plants containing oxalate – sources, Mechanism of toxicity
15	Toxicity of plants containing oxalate – clinical signs, diagnosis and treatment
16	Poisoning due to Strychnos nux-vomica, Ricinus communis and Nerium oleander – Mechanism of toxicity, clinical signs, diagnosis and treatment
17	Poisoning due to Strychnos nux-vomica, Ricinus communis and Nerium oleander – Mechanism of toxicity, clinical signs, diagnosis and treatment
18	Study of plants producing lathyrism
19	Toxicity due to Dhatura alba, Abrus precatorius, Ipomoea carnea – Mechanism of toxicity, clinical signs, diagnosis and treatment
20	Toxicity due to Dhatura alba, Abrus precatorius, Ipomoea carnea – Mechanism of toxicity, clinical signs, diagnosis and treatment
21	Mycotoxins – Hepatotoxins (sporidesmin, aflatoxins and rubratoxins): mechanism of toxicity, symptoms and treatment
22	Mycotoxins – Hepatotoxins (sporidesmin, aflatoxins and rubratoxins): mechanism of toxicity, symptoms and treatment
23	Nephrotoxins (ochratoxin, citrinin): clinical signs and treatment
24	Neurotoxins (penitren A and Patulin): clinical signs and treatment
25	Ergot alkaloids, estrogenism and Trichothecene toxins: clinical signs and treatment
26	Classification of Bacterial toxins: Endotoxins and Exotoxins
27	Bacterial toxins – Diphtheria toxins, Botulinum toxin, Cholera toxin, tetanus toxin, E.coli., Enterotoxin, Endotoxin
28	Bacterial toxins – Diphtheria toxins, Botulinum toxin, Cholera toxin, tetanus toxin, E.coli., Enterotoxin, Endotoxin
29	Bacterial toxins – Diphtheria toxins, Botulinum toxin, Cholera toxin, tetanus toxin, E.coli., Enterotoxin, Endotoxin
30	Snake: types, classification and identification of Poisonous Snakes
31	Toxicity of snake venom – Mechanism of toxicity, clinical signs and treatment
32	Toxicity of snake venom – Mechanism of toxicity, clinical signs and treatment
33	Toxicity due to scorpion – Mechanism of toxicity, clinical signs and treatment
34	Toxicity due to spider and insect stings and toad poisoning – Mechanism of toxicity, clinical signs and treatment
35	Toxicity due to spider and insect stings and toad poisoning – Mechanism of toxicity, clinical signs and treatment
36	Current topics/ Discussion of library assignments

P No.	Name of the topic
1	Detection of alkaloids in toxic plants
2	Detection of glycosides in toxic plants
3	Detection of cyanides in toxic plants
4	Detection of nitrate/ nitrite in toxic plants
5	Detection of tannins in toxic plants
6	Detection of saponins in toxic plants
7	Detection of resins in toxic plants
8	Detection of oxalates in toxic plants
9	Extraction and separation of Phytotoxins
10	Phytochemical analysis of toxic plant extracts
11	Phytochemical analysis of toxic plant extracts
12	Detection of mycotoxins in the samples of feed/ fodder and animal tissue
13	Detection of mycotoxins in the samples of feed/ fodder and animal tissue
14	Identification of toxic weeds and plants of the local area
15	Identification of toxic weeds and plants of the state area
16	Identification of toxic weeds and plants of the state area
17	Collection and dispatch of material for analysis in poisoning cases
18	Toxicants and antidotal therapy
29	Bacterial toxins – Diphtheria toxins, Botulinum toxin, Cholera toxin, tetanus toxin, E.coli., Enterotoxin, Endotoxin
30	Snake: types, classification and identification of Poisonous Snakes
31	Toxicity of snake venom – Mechanism of toxicity, clinical signs and treatment
32	Toxicity of snake venom – Mechanism of toxicity, clinical signs and treatment
33	Toxicity due to scorpion – Mechanism of toxicity, clinical signs and treatment
34	Toxicity due to spider and insect stings and toad poisoning – Mechanism of toxicity, clinical signs and treatment
35	Toxicity due to spider and insect stings and toad poisoning – Mechanism of toxicity, clinical signs and treatment
36	Current topics/ Discussion of library assignments

P No.	Name of the topic
1	Detection of alkaloids in toxic plants
2	Detection of glycosides in toxic plants
3	Detection of cyanides in toxic plants
4	Detection of nitrate/ nitrite in toxic plants
5	Detection of tannins in toxic plants
6	Detection of saponins in toxic plants
7	Detection of resins in toxic plants
8	Detection of oxalates in toxic plants
9	Extraction and separation of Phytotoxins
10	Phytochemical analysis of toxic plant extracts
11	Phytochemical analysis of toxic plant extracts
12	Detection of mycotoxins in the samples of feed/ fodder and animal tissue
13	Detection of mycotoxins in the samples of feed/ fodder and animal tissue
14	Identification of toxic weeds and plants of the local area
15	Identification of toxic weeds and plants of the state area
16	Identification of toxic weeds and plants of the state area
17	Collection and dispatch of material for analysis in poisoning cases
18	Toxicants and antidotal therapy

Course Title : Pharmacological Techniques Course Code : VPT 610 Credit Hours : 0 + 2
Sr. No	Name of the topic
01	Principles of drug
02	Bioassay. Types of bioassay, bioassay techniques
03	Bioassay. Types of bioassay, bioassay techniques
04	Bioassay. Types of bioassay, bioassay techniques
05	Setting up of an isolated tissue preparation and an intact preparation
06	Setting up of an isolated tissue preparation and an intact preparation
07	Study of dose response relationship
08	Study of dose response relationship
09	Supramaximal effect by cumulative dose response study
10	Study on isolated organ assembly
11	Study on isolated organ assembly
12	Study on isolated organ assembly
13	Intact frog heart perfusion
14	Recording of blood pressure in animals
15	Recording of blood pressure in animals
16	Recording of ECG in animals
17	Screening Programme of drugs: General and multidimensional
18	Screening Programme of drugs: General and multidimensional
19	Gross observational methods in Screening procedures
20	Gross observational methods in Screening procedures
21	Calculation of EC50, potency ratio, PDv, PDx PD values
22	Calculation of ED50, TD50 and LD50
23	Screening of hypnotic activity
24	Study of analgesic, antipyretic and anti-inflammatory activity in laboratory animals
25	Study of analgesic, antipyretic and anti-inflammatory activity in laboratory animals
26	Study of general and local anaesthesia in experimental animals
27	Study of anticonvulsant and muscle relaxant effect of drugs
28	Study of anticonvulsant and muscle relaxant effect of drugs
29	Study of antiarrhythmic and antihypertensive action of test compound
30	Study of antiarrhythmic and antihypertensive action of test compound
31	Study of Hypotensive action of test drugs
32	Study of Hypotensive action of test drugs
33	Study of hypoglycemic effect of drugs in rat/rabbits
34	Study of antihyperglycemic and anticholinesteric activity
35	Test of pyrogen using rabbit
36	Guidelines for safety studies of drugs

Course Title : Techniques in Toxicology Course Code : VPT 611 Credit Hours : 0 + 2
P. No	Name of the topic
1	Guidelines for conducting toxicity studies- OECD, WHO, EPA
2	Cell Culture Techniques for Toxicity Assessment
3	Animal Models in Toxicology
4	In vivo Metabolism Studies
5	In Vitro Metabolism Studies
6	Immunotoxicity Testing- cytokine assay
7	Immunotoxicity Testing- Lymphocyte proliferation assay
8	Animal Toxicity Test- Acute Toxicity
9	Liquid Chromatography-Mass Spectrometry (LC-MS) Analysis toxicological samples
10	Animal toxicity tests- subacute toxicity
11	Animal toxicity tests - chronic toxicity
12	Specific toxicity test for neurotoxicity
13	Specific toxicity test for immunotoxicity
14	Specific toxicity test for developmental toxicity
15	Specific toxicity test for behavioral toxicity
16	Genotoxicity and Mutagenicity Testing
17	Ames Test: Detect mutagenic potential using bacterial cultures
18	Micronucleus Assay: Assess chromosomal damage in mammalian cells
19	Comet Assay: Evaluate DNA damage in individual cells
20	Specific toxicity test for reproductive toxicity
21	Specific toxicity test for inhalation toxicity
22	Study-specific toxicity test for carcinogenicity
23	Animal toxicological tests to study metabolism
24	Animal toxicological tests for synergism
25	Animal toxicological tests for the study of antagonisms
26	Good laboratory practices in toxicology
27	Evaluation of the impact of toxic substances on ecosystems
28	Biomarker Analysis in Toxicology
29	Assays for marker enzymes: AchE, GPx, SOD, Catalase
30	Toxicokinetics and pharmacokinetics
31	Analysis of Toxicant in Biological material
32	Biochemical analysis of suspected toxicity specimens
33	Toxicology in Drug Development
34	Hematological evaluation of toxicological samples
35	Environmental toxicology and monitoring techniques
36	Recent techniques in toxicological analysis

Course Title : Ethnopharmacology Course Code : VPT 612 Credit Hours : 1 + 1
Sr. No	Name of the topic
1	History, traditional remedies and regional knowledge in disease cure
2	Alternate systems of medicine in animals
3	Plant drugs with proven pharmacological and therapeutic efficacy
4	Scope of ethnopharmacology
5	Classification and Identification of Medicinal plants
6	Different Phytoconstituents, Classification and Pharmacological profile
7	Indigenous drugs used as antimicrobials
8	Indigenous drugs used as analgesics
9	Indigenous drugs used in CNS disorders
10	Indigenous drugs used in Renal and Urinary tract disorders
11	Indigenous drugs used in eye, ear and skin disorders
12	Therapeutic and adverse effects of potential herbal drugs
13	Therapeutic and adverse effects of potential herbal drugs
14	Current topics/ Discussion of library assignments
15	Current topics/ Discussion of library assignments
16	Standardization and clinical validation of bioactive molecules from plant sources
17	Herbs used as galactagogues, carminatives, antiseptics, antidiarrhoeals, anthelmintics, agents etc
18	Herbs used as Immuno-stimulants, antimicrobials, bioenhancers, analgesics, anti-inflammatory agents

Practical No.	Name of the topic
1	Identification of medicinal plants
2	Selection of Raw Materials - selection of plants (based on ethnopharmacological, chemotaxonomic, geographical, or compound structural bases, environmental factors, and parts of plant selected for extraction)
3	Collection, Identification Authentication of Plant Materials - preservation of herbarium samples, authentication and identification of plant samples
4	Drying of plant Materials by using suitable methods - air drying, microwave heating, oven drying, freeze drying
5	Selection of solvents – selection of solvent for extraction on the basis of solvent power (selectivity), boiling temperature, reactivity, viscosity, safety, cost, vapor pressure, and recovery; classification of the Solvents (polar solvents, semi-polar solvents, non-polar solvents)
6	Methods of Extraction - Maceration, Digestion, Remaceration, Infusion and Decoction
7	Classification, identification and chemical constituents of medicinal plants
8	Preparation of plant extracts in various solvents using different techniques
9	Ethnopharmacological survey
10	Methods of extraction for extracting specific phytoconstituent such as, alkaloids
11	Methods of extraction for extracting specific phytoconstituent such as, alkaloids, carotenoids
12	Methods of extraction for extracting specific phytoconstituent such as, fats and waxes
13	Methods of extraction for extracting specific phytoconstituent such as, glycosides and phenolic compounds, proteins, polysaccharides
14	Evaluation of pharmacological activities of extracts used in animals (Analgesic activity)
15	Evaluation of pharmacological activities of extracts used in animals (Muscle Relaxant activity)
16	Visit to medicinal plant garden
17	Herbal Medicine Regulation and Ethics
18	Herbal Formulation Development

Course Title : Fundamentals of Pharmacokinetics Course Code : VPT 613 Credit Hours : 1 + 1
Sr. No	Name of the topic
1	Dosage forms of drugs
2	Routes of drug administration
3	Transfer of drugs across biological membranes
4	Absorption of drugs
5	Distribution of drugs
6	Biotransformation of drugs
7	Biotransformation of drugs
8	Excretion of drugs
9	Principles of pharmacokinetics
10	Principles of pharmacokinetics
11	Various Pharmacokinetics models
12	Important pharmacokinetic parameters
13	Dosage regiment
14	In-vitro plasma protein binding of drugs
15	PK-PD modelling and Time kill kinetics
16	PK-PD modelling and Time kill kinetics
17	CYP enzymes and their analysis in drug disposition
18	Pharmacokinetic differences in drug metabolism of ruminants and monogastric animals

P. No.	Name of the topic
1	Various methods of drug assay
2	Various methods of drug assay
3	Microbiological assay for antimicrobial drugs
4	Microbiological assay for antimicrobial drugs
5	HPLC techniques
6	HPLC techniques
7	HPLC techniques
8	HPLC techniques
9	Bioavailability of drugs
10	Pharmacokinetics in animal disease models
11	Pharmacokinetics in animal disease models
12	In-vitro plasma protein binding of drugs
13	Determination of different pharmacokinetic parameters
14	Determination of different pharmacokinetic parameters
15	Analysis of pharmacokinetic data
16	Analysis of pharmacokinetic data
17	PK-PD modeling and Time kill kinetics
18	PK-PD modeling and Time kill kinetics

9. Teaching Schedule :UG, PG , PhD – Prepared by – Course Teacher – Year wise / Course
Wise

10. Academic Calendar – UG, PG, PhD -Year wise / Semester Wise

11. College Classes Time Table :UG, PG , PhD – Year wise / Semester Wise

12. Examination Time Table – UG, PG , PhD – Semester / Year wise – Theory and Practical

13. Result –UG, PG , PhD – Semester Wise / Year Wise

Research:

1. List of Research Projects: Completed& Ongoing

Sr. No.	Title of the Project	Name of PI/ Major Advisor/ Research Worker	Funding Agency	Total Cost of the Project (Rs in Lakh)	Extra-mural (Funding Agency)/ Intra-mural	Status (Completed/Ongoing)	Duration
1	Pharmacokinetics of selected drugs in buffaloes	Dr. M. M. Gatne	ICAR		Extramural		1998-2001
2	Establishment of Indigenous drug research Unit	Dr. M. M. Gatne	ICAR		Extramural		1998-2001
3	Acute and subacute toxicity studies of some Bhasmas (co-investigator)	Dr. M. M. Gatne	CCRAS		Extramural	Completed	2006-2007
4	Testing efficacy of antidandruff formulation in dogs	Dr. M. M. Gatne	CCRAS		Extramural	Completed	2008-2009
5	Outreach program on monitoring of drug residues and environmental pollutants	Dr. M. M. Gatne	ICAR		Extramural	Ongoing	2009-2017
1	Outreach Programme on “Monitoring of Drug Residues and Environmental Pollutants”	Dr. Sushant S Sole	ICAR (Indian Council of Agriculture Research)	1,25,93,750	Extramural	Ongoing	2017-till date
7	Acute toxicity of DL Methionine in rats	Dr. Sushant S Sole	UPL Ltd., Mumbai	2,76,500	Extramural	Completed	01 Year
8	Studies on Flunixin OTC	Dr. Sushant S Sole	Bayer Pvt. Ltd. Germany	40,41,752	Extramural	Completed	10 Years
9	Evaluation of effect of RF field during MR scanning in normal and malignant tissues of laboratory animals	Dr. Sushant S Sole	Society For Applied Microwave Electronics Engineering & Research (under Ministry of Communication & IT, Govt of India)	9,84,200	Extramural	Ongoing	02 Years
10	Pharmacokinetic study of clomiphene in buffaloes	Dr. Sushant S Sole	AELPL (Ar-Ex Laboratories Pvt. Ltd), Mumbai	3,01,000	Extramural	Completed	01 Year

2. List of Private Agency Projects:

Sr. No.	Title of the Project	Name of PI/ Major Advisor/ Research Worker	Funding Agency	Total Cost of the Project (Rs in Lakh)	Status (Completed/Ongoing)	Duration
1	Acute toxicity of DL Methionine in rats	Dr. Sushant S Sole	UPL Ltd., Mumbai	2,76,500/-	Completed	01 Year
2	Studies on Flunixin OTC	Dr. Sushant S Sole	Bayer Pvt. Ltd., Germany	40,41,752/-	Completed	10 Years
3	Evaluation of effect of RF field during MR scanning in normal and malignant tissues of laboratory animals	Dr. Sushant S Sole	Society For Applied Microwave Electronics Engineering & Research (an offset of Tata Institute of Fundamental Research, Mumbai, and an R & D institute under Ministry of Communication & IT, Govt of India)	9,84,200/-	Ongoing	02 Years
4	Pharmacokinetic study of clomiphene in buffaloes	Dr. Sushant S Sole	AELPL (Ar-Ex Laboratories Pvt. Ltd.), Mumbai	3,01,000/-	Completed	01 Year

3. Research Priorities:

Sr. No.	Research Area	Aim	Objective	Benefits of Farmers
1.	Drug discovery and new formulation of conventional Drugs / Herbal drugs / plants of Konkan region.
2.	Pharmacokinetics
3.	Regulatory toxicity in rodents and use of zebrafish model for endocrine disruption activities.
4.	Estimation of Drug residues/pesticide residues in biological samples of Konkan region
5.	Development of rodent animal models for different disease conditions e. g. diabetes, arthritis, behavioral models, etc

4. Thesis:
Master:

Name of Department : Veterinary Pharmacology and Toxicology
Sr. No.	Name of the Student	Title of Thesis	Year of Complet ion	Name of the Advisor
1	Dr. M. K. Shingatgeri	Studies Of Record Of Blood Pressure On Normal Dogs By Using Sphygmomanometer	1964
2	Dr. H. V. Jahagirdar	Electrophoretic Studies Of Serum Protein In Infectious Canine Hepatitis	1967
3	Dr. R. D. Sadekar	Studies On The Absorption, Acetylation And Excretion Of Common Sulphonamides In Buffalo Calves	1970	Dr. M. K. Shingatgeri
4	Dr. K. R. Wagh	Pharmacological Studies On Curcuma Longa Linn With Special Reference To Its Anti-Inflammatory Effects In Rats	1972	Dr. M. K. Shingatgeri
5	Dr. S. T. Kalkar	Study Of Some Indigenous Drugs For Their Estrogenic Activity	1976	Dr. M. K. Shingatgeri
6	Dr. M. I. Qureshi	Study On Bioavailability Of Oxytetracycline In Buffaloes	1976	Dr. H. V. Jahagirdar
7	Dr. S. J. Rajahansa	Toxicological Study Of Intravenous Metronidazole In Laboratory Animals	1979	Dr. M. K. Shingatgeri
8	Dr. A. N. Subnis	Study On Propetamphos A New Acaricide With Particular Reference To Its Biological Efficacy, Toxicity To Dogs, And LD50 Determination In Rats	1980	Dr. S. Jagadish
9	Dr. K. Jaykumar	Disposition Of Ampicillin In Serum And Tissue Fluid In Buffalo Calves	1982	Dr. V. V. Ranade
10	Dr. D. S. Naoley	A Preliminary Study On Mercury Residues In Dairy Animals In Thane Kalyan Kalu River Industrial Belt	1983	Dr. H. V. Jahagirdar
11	Dr. M. R. Kulkarni	Toxicological Investigation Of Sulfadiazine-Trimethoprim Combination In Broilers	1983	Dr. H. V. Jahagirdar
12	Dr. R. N. Naik	Studies On The Immunomodulatory Effects Of Levamisole, Indomethacin, And Metronidazole On Immediate Hypersensitivity In Laboratory Animals	1984	Dr. S. Jagadish
13	Dr. G. B. Kulkarni	Droperidol – A Premedicant In Thiopentone Sodium Induced Anaesthesia In Dogs	1984	Dr. H. V. Jahagirdar
14	Dr. H. S. Modak	A Study On Protective Effect Of Indigenous Formulation Against Induced Hepatotoxicity In Albino Rats	1984	Dr. H. V. Jahagirdar
15	Dr. S. G. Burte	Studies On Effects Of Feeding An Indigenous Drug Formulation To Cattle And Poultry	1986	Dr. H. V. Jahagirdar
16	Dr. M. P. Bhalerao	Influence Of Probenecid On Serum Ampicillin Disposition In Dogs	1986	Dr. V. V. Ranade
17	Dr. R. D. Kalkar	Studies On Effects Of Coumaphos And Chlorpromazine Interaction In Cattle	1986	Dr. S. Jagadish
18	Dr. S. Madav	Effect Of Gentamicin On Thiopentone Anaesthesia In Dogs	1986	Dr. S. Jagadish
19	Dr. A. G. Telang	Studies On Interaction Between The Anticonvulsant Drugs Phenytoin And Phenobarbital In Dogs	1988	Dr. S. Jagadish
20	Dr. L. K. Sharma	Comparative Studies Of The Effect Of Levamisole Administration Through Different Routes On Immunomodulation And Anthelmintic Activity In Crossbred Animals	1988	Dr. S. Jagadish
21	Dr. S. S. Panchpor	Therapeutic Evaluation Of Oral And Parenteral Iron Preparations In Experimental Haemorrhagic Anaemia In Crossbred Calves	1989	Dr. V. V. Ranade
22	Dr. S. B. Raut	Pharmacokinetic Studies Of An Injectable Ibuprofen In Dogs And Cattle And Its Safety Assessment To Dogs	1989	Dr. V. V. Ranade
23	Dr. M. T. Raut	Pharmacokinetic Studies And Safety Assessment Of An Injectable-Aspirin In Calves	1990	Dr. V. V. Ranade
24	Dr. S. K. Toke	Studies Of Gentamicin Disposition In Blood And Milk Of Lactating Ewes After Parenteral Administration	1990	Dr. V. V. Ranade
25	Dr. A. P. Pontis	A Study On Lead Levels In Cattle Located Around The Industrial Area Near Udhva And Kalamdevi Villages In Dist-Thane	1991	Dr. V. V. Ranade
26	Dr. P. K. Nemade	Study Of Estrogenic Activity Of Indigenous Test Preparation (Heatinee)	1993	Dr. V. V. Ranade
27	Dr. P. C. Badole	Pharmacokinetic Studies And Safety Assessment Of An Injectable-Tiamulin In Sheep And Goats	1993	Dr. V. V. Ranade
28	Dr. B. B. Gunjate	Study On Efficacy And Safety Of Providone-Iodine In Some Veterinary Clinical Indications	1994	Dr. V. V. Ranade
29	Dr. R. V. Patil	Pharmacokinetic Profile And Safety Assessment Of Pefloxacin Injection In Lactating Cows	1994	Dr. M. M. Gatne
30	Dr. R. Jairam	Pharmacokinetic And Safety Studies Of Injectable Diclofenac Sodium In Buffalo Calves	1995	Dr. V. V. Ranade
31	Dr. S. V. Ingale	Pharmacokinetics Of Enrofloxacin And Its Concentration In Chicken Meat And Eggs	1995	Dr. M. M. Gatne
32	Dr. D. S. Joshi	Hepatoprotective Effect Of Some Herbal And Homoeopathic Drugs In Experimentally Induced Hepatotoxicity In Rats	1996	Dr. M. M. Gatne
33	Dr. R. P. Chandanshive	Pharmacokinetic Studies And Safety Assessment Of Pefloxacin In Lactating Sheep	1996	Dr. V. V. Ranade
34	Dr. N. M. Jare	Pharmacokinetic Profile And Safety Assessment Of Pefloxacin Injection In Lactating Goats	1996	Dr. M. M. Gatne
35	Dr. P. K. Hendre	Pharmacokinetics Of Oral Amoxycillin In Broiler Chickens And Its Comparative Serum Profile After Pulse Dose And Continuous Medication	1997	Dr. M. M. Gatne
36	Dr. S. C. Borkar	Clinical Efficacy And Residue Studies Of Intramammary Infusion Of Enrofloxacin In Mastitic Buffaloes	1998	Dr. M. M. Gatne
37	Dr. D. A. Deshpande	Study Of Serum Disposition Of Long-Acting Ampicillin In Cow And Buffalo Calves	1998	Dr. V. V. Ranade
38	Dr. A. H. Pawar	Clinical Evaluation And Passage Of Enrofloxacin Across Uterus In Repeat Breeding Buffaloes	1999	Dr. V. V. Ranade
39	Dr. V. S. Shinde	Pharmacokinetic Studies Of Chloramphenicol In Buffaloes	1999	Dr. M. M. Gatne
40	Dr. S. S. Pawar	Disposition Of Paracetamol In Serum And Cerebrospinal Fluid In Buffaloes	1999	Dr. M. M. Gatne
41	Dr. D. A. Kamble	Pharmacokinetic Study Of Amoxycillin And Its Disposition In Cerebrospinal Fluid And Urine In Buffalo Calves After Intravenous Administration	2000	Dr. M. M. Gatne
42	Dr. P. A. Patil	Pharmacokinetic Studies Of Cefotaxime And Its Disposition In Cerebrospinal Fluid And Urine In Buffalo Calves After Intravenous Administration	2000	Dr. M. M. Gatne
43	Dr. C. M. Khdadtare	Studies On Influence Of Shatavari (Asparagus Racemosus) Feeding On Milk Production In Animals	2000	Dr. A. P. Somkuwar
44	Dr. S. R. Giri	Studies On Disposition Kinetics Of Oxytetracycline In Buffalo Calves By I.M. And I.V. Routes And Its Interaction With I.V. Calcium	2001	Dr. M. D. Deore
45	Dr. P. P. Gaikwad	Pharmacokinetics Of Ceftrioxone And Its Disposition In Various Body Fluids In Buffalo-Calves	2001	Dr. M. M. Gatne
46	Dr. M. M. Mehendale	Pharmacokinetic Studies On Diminazene In Buffalo Calves	2001	Dr. M. D. Deore
47	Dr. S. R. More	Pharmacokinetics Of Ceftriaxone And Its Urinary Excretion In Goats	2002	Dr. M. M. Gatne
48	Dr. A. M. Dafe	Efficacy Of Combination Of Mannan Oligosaccharide, Organic Acids, Zeolite And Activated Charcoal On Performance And During Induced Alfatoxicosis In Chickens	2002	Dr. M. M. Gatne
49	Dr. C. Lalmuanthanga	Pharmacokinetic Studies On Long Acting Enrofloxacin And Its Comparison With Conventional Enrofloxacin After Single Intramuscular Administration In Cow Calves	2002	Dr. M. D. Deore
50	Dr. K. M. Telang	Clinical Efficacy Of Spot On Formulation Of Fipronil In Dogs Infested With Ticks And Fleas And Its In Vitro Efficacy Against Common Dog Tick Rhipicephalus Sanguineus	2003	Dr. M. M. Gatne
51	Dr. S. B. Khobragade	Pharmacokinetics And Urinary Excretion Of Amikacin In Calves	2003	Dr. M. D. Deore
52	Dr. B. D. Ghanshyam	Pharmacokinetics Of Ceftiofur And Its Urinary Excretion In Buffalo Calves	2004	Dr. M. M. Gatne
53	Dr. S. S. Dadarkar	Clinical Evaluation And Toxicity Studies Of Long Acting And Conventional Formulation Of Ivermectin	2004	Dr. M. D. Deore
54	Dr. D. P. Vaijnathrao	Pharmacokinetics Of Ceftiofur In Chickens	2005	Dr. M. D. Deore
55	Dr. A. M. Patil	Isobologram Analysis Of Amoxicillin And Cloxacillin Combination Against Some Bacterial Isolates Of Veterinary Importance	2005	Dr. M. D. Deore
56	Dr. P. S. Bhoir	Pharmacokinetics And Disposition Of Ceftiofur In Various Body Fluids In Buffalo	2005	Dr. M. M. Gatne
57	Dr. Ramesh	Isobologram Analysis Of Combination Of Sulfamethoxazole And Trimethoprim Against Some Bacterial Isolates Of Veterinary Importance	2005	Dr. M. M. Gatne
58	Dr. S. R. Malsure	Pharmacokinetics Of Danofloxacin In Buffaloes	2006	Dr. M. M. Gatne
59	Dr. V. D. Suryawanshi	Efficacy Of Combination Of Organic Acids Against Experimentally Induced Gout In Chicken	2006	Dr. M. M. Gatne
60	Dr. D. S. Jondhale	Studies On Antiviral Activity Of Mangrove Plant Acanthus Ilicifolius In Poultry	2006	Dr. M. D. Deore
61	Dr. S. P. Chawade	Pharmacokinetics Of Sparfloxacin In Broiler Chicken	2007	Dr. M. D. Deore
62	Dr. Elizabeth Kimtei	Toxicity And Residue Study Of Florfenicol In Chicken	2008	Dr. M. M. Gatne
63	Dr. N. S. Adsul	Pharmacokinetics And Efficacy Of Different Formulations Of Florfenicol In Chicken	2008	Dr. M. M. Gatne
64	Dr. P. S. Gurav	In Vitro Screening Of QT Prolonging Drugs For Their Arrhythmogenic Potential In Isolated Rabbit Heart	2009	Dr. M. M. Gatne
65	Dr. G. R. Ghangale	Neuroprotective Effect Of Peroxisome Proliferator-Activated Receptor–Gamma Agonist And Statin On Cerebral Ischemia And Reperfusion Induced Cerebral Injury In Rats	2009	Dr. M. M. Gatne
66	Dr. K. Anbarasan	Efficacy Of Phyllanthus Niruri Against Induced Newcastle Disease Virus Infection In Chicken	2009	Dr. M. M. Gatne
67	Dr. G. H. Chaudhari	Screening Of QT Prolonging Drugs For Their Arrhythmogenic Potential In Anaesthetized Rabbit	2009	Dr. M. M. Gatne
68	Dr. S. P. Tamhankar	Studies On Antigenotoxic Effect Of Withania Somnifera In Rats	2009	Dr. M. M. Gatne
69	Dr. V. S. Surve	Studies On Antigenotoxic Effect Of Terminalia Arjuna In Rats	2009	Dr. M. M. Gatne
70	Dr. T. R. Mahale	Developmental Immunotoxicity Of Allopurinol In Mice	2010	Dr. M. M. Gatne
71	Dr. L. B. Gawade	Developmental Immunotoxicity Of Imidacloprid In Mice	2010	Dr. M. M. Gatne
72	Dr. A. G. Somwanshi	Developmental Immunotoxicity Of Fipronil In Mice	2010	Dr. M. M. Gatne
73	Yadav Manish Hansraj	Evaluation Of Protective Effect Of Vitex Negundo (Nirgundi) On Induced Osteoarthritis In Wistar Rats	2011	Dr. M. M. Gatne
74	Paranjape Vaidehi Vijay	Efficacy Of Terminalia Arjuna In Dilated Cardiomyopathy And Valvular Heart Disease In Dogs	2011	Dr. M. M. Gatne
75	Kalaskar Pankaj Suryakant	Antifungal Activity Of Acanthus Ilicifolius Leaves In Induced Aspergillosis In Mice	2011	Dr. M. M. Gatne
76	Kale Rushikesh Pandurang	Evaluation Of Antimicrobial Residues In Poultry Eggs By ELISA	2012	Dr. M. M. Gatne
77	Gatne Akshada Mukulesh	Evaluation Of Cardiotoxic Potential Of Some Veterinary Drugs In Zebrafish	2012	Dr. V. V. Karande
78	Pandure Dinesh Ramesh	Detection Of Some Heavy Metal Residues In Seafoods Of Mumbai & Thane Region	2012	Dr. M. M. Gatne
79	Kauthale Rahul Ramdas	Evaluation Of Some Drugs Used In Veterinary Medicine	2013	Dr. V. V. Karande
80	Tambe Kirti Balkrishna	Anti-Angiogenic Potential Of Herbal Drugs On Zebrafish Model	2014	Dr. M. M. Gatne
81	S. Pfokrehrii	Pharmacokinetic Study Of Cephalexin In Broiler Chickens	2014	Dr. M. M. Gatne
82	Joge Puja Arun	Evaluation Of Anti-Angiogenic Potential Of Herbal Drug In Mouse Model	2015	Dr. M. M. Gatne
83	Puri Devika Sandeep	Pharmacokinetic Study Of Clomiphene In Goats	2015	Dr. M. M. Gatne
84	Ashwini Kumar Sharma	Bioavailability Of Vitamin C From Kokum (Garcinia Indica) And Its Efficacy Against Heat Stress In Poultry	2015	Dr. V. V. Karande
85	Anna Maria Joy	Hazardous Potential Of Endocrine Disruptors On Reproduction In Male Zebrafish	2016	Dr. M. M. Gatne
86	Rajeev Jeenger	Possible Antiangiogenic Synergism Between Eugenol And Tyrosine Kinase Receptor Inhibitor In Murine Model	2016	Dr. M. M. Gatne
87	Gavali Sandeep Nandkumar	Antimicrobial Activity Of Extracts Of Selected Plants Against Multi Drug Resistant Staphylococcus Aureus Isolated From Bubaline Mastitis	2017	Dr. V. V. Karande
88	Bhalerao Shrikant Tulsidas	Possible Endocrine Disrupting Effect Of Deltamethrin On Male Zebrafish And Its Effect On Embryo Development	2017	Dr. M. M. Gatne
89	Palamate Parameshwar Sunil (V/10/016)	Detection of some heavy metals in dog serum from Mumbai and Thane area	2017	Dr. V.V. Karande
90	Jyoti Gautam (V/15/286)	Development toxicity of some veterinary drugs in zebrafish (Danio Rerio) embryos	2017	Dr. M. M. Gatne
91	More Priyanka Shankar (V/10/066)	Determination of clophene isomers by liquid chromatography –mass spectrometry method in caprine plasma after its single intramuscular administration	2017	Dr. V.V. Karande
92	Yadav Krishnakumar Ramsevak	Evaluation of Ayurvedic Formulation Amrutadi on rheumatoid arthritis model in rat	2019	Dr. S.S. Sole
93	Kambli Ashvini Pradeep	Assessment of toxic metal in buffalo milk samples from Mumbai suburbs	2018	Dr. S.S. Sole
94	Bagal Niranjan Dattatraya	Pharmacokinetic study of Isoniazid in cow (calf)	2018	Dr. S.S. Sole
95	Lonare Snehal	Assessment of Ractopamine for endocrine dysfunction and teratogenic effects in zebrafish	2018	Dr. S.S. Sole
96	Subhdar Irfan Hameed	Ionophore Combination and Selamectin: Evaluation for endocrine dysfunction and non-target toxicity in zebrafish	2019	Dr. S.S. Sole
97	Kambale Kunal Sandipan	Monitoring of heavy metals in buffalo milk and water samples from industrialized zones of Mumbai suburbs and Konkan region	2019	Dr. S.S. Sole
98	Krutika Pramod Khairatkar	Validation of method and pharmacokinetic assessment of formaldehyde in various animal origin products by reverse-phase high-pressure liquid chromatography (HPLC)	2021	Dr. S.S. Sole
99	Patil Pradnya Netaji	Evaluation of Fluralaner for endocrine disruption and embryonic toxicity in zebrafish model	2021	Dr. S.S. Sole
100	Karhale Vitthal Sudam	Evaluation of therapeutic potential of Bleomycin and Catechin combination in animal model of mammary tumor	2023	Dr. S.S. Sole
101	Sahil Raman	Pharmacokinetic study of Levefloxacin and Flunixin and their interaction in goat	2023	Dr. S.M. Ghadigaonkar
102	Mote Vishal Parabati	Evaluation of efficacy of Enrofloxacin and Catechin on chronic bacterial prostatitis rat model	2024	Dr. S.S. Sole
103	Purva Joshi	Efficacy of Curcuma Longa L. and Terminalia Chebula Retz. against DNCB-induced atopic dermatitis in mice	2024	Dr. S.M. Ghadigaonkar

Doctoral:

Sr. No.	Name of the Student	Title of Thesis	Year of Completion	Name of the Advisor
1	Giri Suresh Ramakant	Cardioprotective role of peroxisome proliferator activated receptor (PPAR) agonist in preclinical models	2014	Dr. M. M. Gatne
2	Karande Vikas Vasant	Studies on resistance pattern to Beta-lactam antibiotics in Staphylococcus-aureus and Escherichia coli isolated from milk of buffaloes with mastitis	2017	Dr. M. M. Gatne

5. Research Papers Published:
List of Research Publications:

Sr.No.	Authors	Year	Title of the Research Paper	Name of the Journal	Volume; Page Nos.	NAAS Rating, if any
1	M. M. Gatne, V. V. Ranade and S. Jagadish	1991	Influence of probenecid on serum ampicillin disposition in dogs.	Indian Vet. J.	67: 506-508
2	V. V. Ranade and M. M. Gatne	1990	A modified technique for perfusion of goat mammary gland for studying antibiotic concentration in milk.	Bombay Vet. Coll.	2 (1): 57-59
3	S. D. Mahashabde, S. Jagadish, M. M. Gatne and V. V. Ranade	1993	Serum disposition of long acting and double strength conventional formulation of oxytetracycline in buffaloes.	Indian Vet. J.	69 (12): 1147-1148
4	M. M. Gatne, A. G. Telang, S. K. Toke and V. V. Ranade	1992	Safety assessment of injectable neomycin in calves.	Hindustan Antibiotics Bulletin	34 (3-4): 108-109
5	M. M. Gatne, S. K. Toke, R. D. Kalkar and V. V. Ranade	1993	Pharmacokinetics of neomycin in calves.	Indian Vet. J.	70: 422-425
6	S. B. Raut, S. Jagadish, M. M. Gatne, M. D. Deore and V. V. Ranade	1993	Pharmacokinetic studies of an injectable Ibuprofen in cattle.	Indian Vet. J.	70 (11): 1008-1010
7	M. D. Deore, S. Jagadish, M. M. Gatne, S. B. Raut and V. V. Ranade	1993	Effect of metoclopramide on plasma disposition of paracetamol in dogs.	J. Bombay Vet. College	4 (1&2): 13-16
8	S. K. Toke, M. M. Gatne, P. K. Nemade and V. V. Ranade	1993	Studies on serum gentamicin disposition after parenteral administration in ewes.	Hindustan Antibiotics Bulletin	Aug. Nov., 1993
9	M. M. Gatne, P. C. Badole and V. V. Ranade	1994	Pharmacokinetics of Tiamulin in calves after single intramuscular administration.	Indian Vet. J.	71 (11): 1148-1149
10
11	M. M. Gatne, P. C. Badole and V. V. Ranade	1995	Pharmacokinetics of Tiamulin in sheep after single intramuscular administration.	Indian Vet. J.	72 (3): 287-289
12	R. V. Patil, M. M. Gatne, A. P. Somkuwar and V. V. Ranade	1996	Pharmacokinetics and milk concentration of Pefloxacin injection (PELWIN) in lactating cows	Indian Vet. J.	73 Nov.1996: 1130-1132
13	M.M.Gatne	1999	Disposition of Enrofloxacin in some biological fluids of buffaloes	Thesis submitted for award of Ph. D. to Konkan Krishi Vidyapeeth, Dapoli, Dist. Ratnagiri
14	V.V.Ranade, M.M.Gatne	2001	Fluoroquinolones	In “Veterinary Pharmacology and Toxicology, ed. B.K.Roy, Kalyani publishers, New Delhi
15	Mehedndale M.M., Gatne M.M. and Deore M.D.	2001	In-vitro erythrocytic partitioning of diminazene in buffaloes	J. Bom. Vet. Coll.	9 (1&2), 13-14
16	S.R.Giri, M.D.Deore and M.M.Gatne	2001	Disposition kinetics of Oxytetracycline in buffalo calves	J.Vet. Pharmacol. Toxicol.	Vol. 1, 30-33
17	Pawar S.D., A.P.Somkuwar, M.D.Deore and M.M.Gatne		Evaluation of Emblica officinalis for its anti-inflammatory activity in rats	J. Bom. Vet. Coll.	10 (1&2), 12-14
18	Pawar S.D., Somkuwar A.P., Deore M.D. and Gatne M.M.	2003	Evaluation of galactogogue effect of a herbal preparation in nursing rats and buffaloes	J. Bomb. Vet. Coll.	11(1&2), 6-8
19	Khobragade S.B., Deore M.D. and Gatne M.M.	2003	Safety evaluation of amikacin after its repeated administration for five days in buffalo calves	Bomb. Vet. Coll.	11(1&2), 52-53
20	S.D. Pawar, A.P. Somkuwar, M.D.Deore and M.M. Gatne	2003	Effect of Awala on carbon tetrachloride induced hepatotoxicity in rats	Toxicology International	10(2): 12-23
21	Pawar S.D., Somkuwar A.P., Deore M.D. and Gatne M.M.	2004	Clinical evaluation of Emblica officinalis for its activity against liver disorders in cattle	J. Bomb. Vet. Coll.	12(1&2): 15-16
22	Lalmuanthanga, M.D. Deore, M.M. Gatne and S.B. Khobragade	2005	Pharmacokinetic studies on long acting and conventional Enrofloxacin in cow calves	Indian Vet. J	82 : 943-946
23	M.D. Deore, S.S. Dadarkar, D.G. Bakre and M. M. Gatne	2005	Toxicity studies of Metoprolol succinate after repeated oral exposure in albino rats	Toxicol. Int.	12(2): 101-107
24	M.D. Deore, M.M. Gatne and S.D. Pawar	2005	Hepatoprotective effect of ‘Livovet’ on mycotoxin induced liver damage in poultry	J. Vet. Pharmacol. Toxicol.	4(1-2): 10-14
25	M.M.Gatne, Ramesh, P.S. Bhoir, M. D. Deore	2006	Immunotoxicity studies of imidacloprid in rats	Toxicology International	13 (2): 89-92
26	P.C.Badole, V.V.Ranade, M.M.Gatne and A.P.Somkuwar	2005	Pharmacokinetics of Tiamulin in goats after single intramuscular administration	The Royal Veterinary Journal Of India	Vol.1(1): 55
27	Dadarkar S.S., Deore M.D., Gatne M.M.	2006	Preliminary evaluation of a polyherbal formulation for its galactogogue properties in primiparous wistar rat	J. Bombay Veterinary College	13
28	Dadarkar S.S., Deore M.D., Gatne M.M.	2007	Comparative evaluation of acute toxicity of ivermectin by two methods after single subcutaneous administration in rats	Regulatory Toxicology Pharmacology, INPRESS
29	Sonali R Naikwade, Amrita N Bajaj, Prashant Gurav, Madhumanjiri M Gatne, and Pritam Singh Soni	2009	Development of Budesonide Microparticles Using Spray-Drying Technology for Pulmonary Administration: Design, Characterization, In Vitro Evaluation, and In Vivo Efficacy Study	AAPS Pharm Sci Tech
30	P.V. Deshmukh, P.C. Badgujar, and M.M. Gatne	2009	In-vitro red blood cell partitioning of doxycycline	Indian J Pharmacol		August; 41(4): 173–175
31	Sushant Sole	2017	“Microbial Terrorism: Need for Call to Action in Livestock”	EC Pharmacology and Toxicology	4.3 (2017): 118-119
32	Lalita Bhalerao, Sushma Shendre-Ghadigaonkar	2018	Effect of ethanolic leaf extract Aegle marmelos (L.), Correa gentamicin induced nephrotoxicity in Wistar rats	Journal of Veterinary on Pharmacology and Toxicology	17(2): 13-16
33	S. M. Lonare, S. S. Sole and S. A. Umap	2018	Exposure to Ractopamine Induces Behavioural and Reproductive Alterations in Zebrafish (Danio rerio)	Toxicology International	Vol 25(3): 31-42
34	Supriya Pandurang Mortale, Ramdas Ganpatrao Bhong, Sushant Shivdas Sole and Sankunny Mohan Karuppayil	2018	Phytochemicals Improve Anti-inflammatory Activity of Diclofenac in Rat Paw Edema Model	Pharmacologia
35	S. Y. Shirale, H. Y. Palampalle, B. S. Khillare, S. B. Majee, D. P. Kadam, and S. S. Sole	2018	Prevalence Of Trypanosomosis In Buffaloes Of Mumbai Region	Contemporary Research in India	(ISSN 2231-2137): Vol. 8: Issue: 3
36	Ashwini Kambli, Sushant Sole, Kaustubh Garud, Snehal Lonare, Niranjan Bagal	2019	Quantitative Analysis of Toxic Metals in Buffalo Milk Samples from Mumbai Suburban Region by ICP-AES	AES. J. Anim. Health Prod	(1): 5-10
37	Niranjan Bagal, Sushant Sole, Swati Umap, Ashwini Kambli, and Kunal Kamble	2020	Disposition of Isoniazid by Oral and Intravenous Administration in Cow Calf using RP-HPLC Method	Int. J. Curr. Microbiol. App. Sci	9(9): 1577-1585
38	Umesh Kannamangalam Vijayan, Sadineni Varakumar, Sushant Sole, and Rekha S. Singhal	2020	Enhancement of loading and oral bioavailability of curcumin loaded self-microemulsifying lipid carriers using Curcuma oleoresins	Drug Development and Industrial Pharmacy	DOI: 10.1080/03639045.2020.1762201
39	Niranjan Bagal, Sushant Sole, Swati Umap, Ashwini Kambli, and Kunal Kamble	2020	Ozone therapy: An important approach in veterinary therapeutics	Journal of Veterinary Pharmacology & Toxicology	June 2020 / Vol. 19 / Issue 1 / 1-7
40	Sushma Ghadigaonkar, A.G. Reddy, B. Kala Kumar, M. Lakshman, and U. Rajkumar	2021	Quantification of total phenolic content, total flavonoid content, and evaluation of in-vitro free radical scavenging activities in Ficus religiosa Linn.	The Pharma Innovation Journal	10(3): 84-88
41	V. Garud Kaustubh, Y. Buduk Shreya, A. Deosthali Samruddhi, N. Galdhar Chandrakant, S. Sole Sushant, D.A. Pawalkar, and V. Gaikwad Rajiv	2021	Assessment of antibiotic sensitivity patterns of bacterial isolates in dogs with positive urine cultures with and without renal dysfunction and variable urinary tract signs	Indian J. Vet. Med.	Vol. 41, No. 1, 2021, pp. 15-21
42	Sushma Ghadigaonkar, A. Gopala Reddy, B. Kala Kumar, and B. Anil Kumar	2021	Screening of antioxidant and free radical scavenging activities of Terminalia arjuna Roxb	The Pharma Innovation Journal	10(2): 01-05
43	Santosh Tambade, Sushma Ghadigaonkar	2021	Nephroprotective effect of ethanolic extract of Pedalium murex in cisplatin-induced nephrotoxicity in Wistar rats	The Pharma Innovation Journal	SP-10(6): 607-610
44	Sushma Ghadigaonkar, A. Gopala Reddy	2021	Cardioprotective effect of aqueous leaf extract of Ficus religiosa Linn on 5-FU-induced toxicity in rat	The Pharma Innovation Journal	10(12): 412-416
45	Shubhangi Nimbore, Sushma Ghadigaonkar	2021	In-vitro and In-vivo evaluation of the antibacterial activity of ethanolic and aqueous leaf extract of Murraya Koengii in mice	The Pharma Innovation Journal	10(7): 226
46	Sushma Ghadigaonkar, A. Gopala Reddy, B.D.P. Kala Kumar, and M. Lakshman	2021	Ameliorating Effect of Terminalia arjuna Against 5-Fluorouracil Induced Cardiotoxicity in Wistar Rats	Acta Scientific Veterinary Sciences	Volume 3, Issue 9, September 2021: 75-79
47	Sushma Ghadigaonkar, A. Gopala Reddy, B. Kala Kumar, M. Lakshman, Shiva Kumar, and Anudeep Reddy	2021	Evaluation of Ficus religiosa in Comparison to Captopril against Experimental Cardiotoxicity due to 5-Fluorouracil in Rats	Acta Scientific Veterinary Sciences	3.9: 49-54
48	Pradnya Patil, Sushant S. Sole, Purva Joshi, Vishal P. Mote, R.V. Gaikwad, S.U. Gulavane, and P.V. Meshram	2023	Exposure to Fluralaner induces behavioral and reproductive alterations in Zebrafish (Danio rerio)	The Pharma Innovation Journal	12(2): 2228-2238
49	S.S. Sole, Vishal P. Mote, Purva Joshi, and Ravindra Ambade	2023	Controlled Release acarbose beads ameliorates ruminal function for extended time	Journal of Veterinary Pharmacology & Toxicology	June 2023, Vol. 22, Issue 1, 18-21
50	Sushma Ghadigaonkar, A. Gopala Reddy	2022	5-FU induced cardiotoxicity amelioration by aqueous leaf extract of Ficus religiosa	Acta Scientific Veterinary Sciences	4.1: 179-185
51	Sahil Raman, S.M. Ghadigaonkar, S.S. Sole, R.V. Gaikwad, K.V. Garud, and H.Y. Pallampalle	2023	Pharmacokinetics Study of Levofloxacin in Goats	Trends in Agriculture Science	2(11), Nov 2023: 1036-1044
52	V.S. Karhale, S.S. Sole, S.M. Ghadigaonkar, R.V. Gaikwad, P.V. Meshram, S. Bharucha, V.P. Mote, P. Joshi, S.S. Jadhav, and H.Y. Palampalle	2024	Catechin enhances the antitumour activity of Bleomycin in DMBA-induced mammary carcinoma in rats	International Journal of Veterinary Sciences and Animal Husbandry	9(1): 163-169
53	Sushma Ghadigaonkar	2023	Evaluation of the antibacterial activity of ethanolic and aqueous leaf extract of Hibiscus rosa-sinensis in mice	The Pharma Innovation Journal	12(1): 27-30
54	V.S. Karhale, S.S. Sole, S.M. Ghadigaonkar, R.V. Gaikwad, P.V. Meshram, S. Bharucha	2024	Catechin enhances the antitumor activity of Bleomycin in DMBA-induced mammary carcinoma in rats	International Journal of Veterinary Sciences and Animal Husbandry	9(1): 163-169
55	Gavali Sandeep, Karande Vikas, Ghadigaonkar Sushma, and Joshi Purva	2024	Plant-derived drug against drug-resistant Staphylococcus aureus	International Journal of Veterinary Sciences and Animal Husbandry	9(1): 216-223
56	Sushant S. Sole, Kunal S. Kambale, Rajiv V. Gaikwad, and Promod V. Meshram	2025	ICP AES assessment of lead, mercury, and determination of impact on animal productivity	International Journal of Biology Sciences	7(1): 28-35

List of Marathi and Popular articles published:

Sr.No	Authors	Year	Title	Name of the Journal/Magazine
1	डॉ. आर. बी. अंबादे, डॉ. एस. एस. सोले	2023	'लम्पी स्किन' मुळे होणाऱ्या जैवरसायनिक बदलांवर उपचार
2	Dr. S S Sole, Dr. R B Ambade	2022	Mumbai Veterinary College holds animal vaccination drive for Lumpy Skin disease	D- Voice, Oct 19, 2022, Online News, https://dvoice.in/mumbai-veterinary-college-holds-animal-vaccination-drive-for-lumpy-skin-disease/
3	Dr. S S Sole	2024	Microbial encroachment: an insight required for therapy policies	Vet Farm Frontier e-Magazine, April 2024/ Vol. 1/ Issue 2/ 13-15
4	Dr. S S Sole	2024	Antibiotics adverse effects in animals due to indiscriminate use izfrtSfodkaP;k vfrokijkpk tukojkaoj ifj.kke	AGROWON Newspaper 15 October 2024

6. Research Recommendations

Sr.No
Year
Project Title
Investigators
Recommendations

7. MOU signed by the Colleges

Sr. No.	MOUS Between Party - I & Party - II	Date of Signing	Place	Duration

8. Research Priorities / Thematic areas: Department Wise

Drug discovery and new formulation
pharmacokinetics
Conventional drugs/ Herbal drugs/plants of Konkan region.
Regulatory toxicity in rodents and use of zebrafish model for endocrine
disruption activities.
Estimation of Drug residues/pesticide residues in biological samples of
Konkan region.
Development of rodent animal models for different disease conditions
e. g. diabetes, arthritis, behavioral models, etc.

9. Significant Research Achievement:

Sr. No.	Achievements	Description
1	Patents Awarded
2	Breed Registration
3	IPR
4	Copyright
5	Trademark

Extension:

Field and other activities undertaken by faculty:

1. Training Organized

Farmers

Sr. No.	Name of Training / Title of Training	Duration From … to …	No. of Participants	Name of Faculty
1	NABL AWARENESS	01 st December 2021 to 04 th December 2021	10	Dr.Sushant.S.Sole

Officers

Sr. No.	Name of Training	Duration From … to …	No. of Participants	Name of Faculty

2. Conference s / Workshop / Seminars / Webinars / Farmers meet organized

Farmers

Sr. No.	Title of workshop, Seminar, Farmers meet	Place	Date	No of participants
1

Officers

Sr. No.	Title of workshop, Seminar, Farmers meet	Place	Date	No of participants

3. Adopted/ Operational Villages

Sr. No.	Name of Adopted Village	Type of Extension Activity	Brief Description (Guests, Resource Persons, Faculty Involved, No. of Participants)

Student Corner:

1. Awards / Recognitions:

Sr. No.	Name of Student	Name of Award / Achievement	Place	Date	Awarding Agency

2. NSS:
Regular / Special Camp (Year Wise)

Sr. No.	Regular / Special	No of Student Registered	No. of Student Present	Place	Name of Activity	Name of Expert

3. Photo Gallery (NSS )

Department:

Achievements of the Department: [Chronology as per the MAFSU Statute]
( PDF format)

1. No. of PG students graduated : 103
2. Research Publications: 56
3. Books/ Chapters:
4. No. of research schemes and agency funded projects completed:4
5. No. of awards
6. Radio talks : 6
7. TV Talks : 1
8. Marathi and Popular publications : 4
9. Any other achievement by the faculty and student: Young Scientist Award Dr.S.S.Sole

Faculty:

Name of Department: Veterinary Pharmacology and Toxicology
Brief History of Department: Department of Pharmacology and Toxicology was
established in 1961. Post-graduate study programme started in the year 1972. Ph. D.
degree programme partly by papers and partly by research has been instituted from the
year 2004. So far 83 candidates completed M.V.Sc. successfully and two have completed
Ph.D. by research.
Laboratory Facilities in the Department:
Diagnostic services offered by the department:
Faculty : (Department Wise) – [ Chronology as per the MAFSU Statute ]

Academic officer:

Sr No	Name of Academic Officer	Qualification	Designation	Email ID	Contact No	Link to Digital Profile
1	Dr. Sushma Mangesh Ghadigaonka r	PhD	Assistant Professor	sushmaghadigaonkar@mafsu.ac.i n	860084443 0
2	Dr. Sushant Shivdas Sole	PhD	Assistant Professor	sushantsole@mafsu.ac.in	830830538 9

Academic staff:

Sr No	Name of Academic Staff	Qualification	Designation	Email ID	Contact No	Link to Digital Profile

Ministerial staff:

Sr. No	Name of Ministerial Staff	Department	Email

List of retired faculty: (Department wise)

Sr. No.	Name of the Staff	Designation	Duration
1.	Dr. M. K. Joshirao	Professor	1962-1964
2.	Dr. M. K. Shingatgeri	Professor	1965 – 1986
3.	Dr. H. V. Jahagirdar	Professor	1979 – 1986
4.	Dr. S. Jagadish	Professor	Aug. 1986 – Nov. 1987
5.	Dr. V. V. Ranade	Professor	Nov. 1987 – March 1999
6.	Dr. M.D. Deore	Associate Professor - resigned	1996 - 2007
7.	Londhe B. B.	Professor	2000-2003
8.	Dr. Madhumanjiri M. Gatne	Professor	2003 – 2017